Fluoxetine

Also known as: (±)-N-methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine, N-methyl-3-phenyl-3-(4-trifluoromethylphenoxy)propan-1-amine, dl-3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine, Adofen, Fluctin, Fluoxeren, Fluval, Foxetin, Reneuron, AURORA KA-7692, METHYL-[3-PHENYL-3-(4-TRIFLUOROMETHYLPHENOXY)PROPYL]AMINE

Fluoxetine (CAS 54910-89-3) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H18F3NO and a molecular weight of 309.326 g/mol. Key properties include a melting point of 158ºC, a boiling point of 395.1±42.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 192.8±27.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 54910-89-3
Jingsj CID: J-2752-6
Molecular Formula: C₁₇H₁₈F₃NO
Molecular Weight: 309.326 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	158ºC
Boiling Point	395.1±42.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	192.8±27.9 °C
Exact Mass	309.134064
PSA	21.26000
LogP	4.09
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.511

Activity & Biological Data

Additional Information	[1]. Malberg JE, et al. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology. 2003 Sep;28(9):1562-71 [2]. Kodama M, et al. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biol Psychiatry. 2004 Oct 15;56(8):570-80. [3]. Wang JW, et al. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci. 2008 Feb 6;28(6):1374-84. [4]. Bymaster FP, et al. Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl). 2002 Apr;160(4):353-61 [5]. Zhang W, et al. Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex. Neuropsychopharmacology. 2000 Sep;23(3):250-62. [6]. Avitsur R1. Increased symptoms of illness following prenatal stress: Can it be prevented by fluoxetine? Behav Brain Res. 2017 Jan 15;317:62-70.

Additional Information

[1]. Malberg JE, et al. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology. 2003 Sep;28(9):1562-71 [2]. Kodama M, et al. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biol Psychiatry. 2004 Oct 15;56(8):570-80. [3]. Wang JW, et al. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci. 2008 Feb 6;28(6):1374-84. [4]. Bymaster FP, et al. Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl). 2002 Apr;160(4):353-61 [5]. Zhang W, et al. Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex. Neuropsychopharmacology. 2000 Sep;23(3):250-62. [6]. Avitsur R1. Increased symptoms of illness following prenatal stress: Can it be prevented by fluoxetine? Behav Brain Res. 2017 Jan 15;317:62-70.

Customs & Trade Information

HS Code	29036990

Frequently Asked Questions

What is the CAS number of Fluoxetine?

The CAS number of Fluoxetine is 54910-89-3.

What are the molecular formula and molecular weight of Fluoxetine?

Fluoxetine has molecular formula C17H18F3NO and molecular weight 309.326 g/mol.

What are the upstream and downstream products of Fluoxetine?

For Fluoxetine, Upstream Products: 3-Hydroxy-N-methyl-3-phenyl-propylamine, 4-Chlorobenzotrifluoride, Ethyl N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]carbamate; Downstream Products: Fluoxetine hydrochloride, R-(-)-Fluoxetine hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Fluoxetine (CAS 54910-89-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2752-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.