Lificiguat

Also known as: YC-1, 1-Benzyl-3-(5-hydroxymethylfur-2-yl)indazole, 1-benzyl-3-(5-hydroxymethyl-furan-2-yl)indazole, 5-[1-(Phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol, Nsc728165

Lificiguat (CAS 170632-47-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H16N2O2 and a molecular weight of 304.342 g/mol. Key properties include a boiling point of 522.2±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 269.6±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 170632-47-0
Jingsj CID: J-27364-3
Molecular Formula: C₁₉H₁₆N₂O₂
Molecular Weight: 304.342 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	522.2±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	269.6±30.1 °C
Exact Mass	304.121185
PSA	51.19000
LogP	3.55
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.653

Activity & Biological Data

Target	Kd: 0.6-1.1 μM (sGC, in the presence of CO)[1]
Additional Information	[1]. Purohit R, et al. YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. Biochemistry. 2014 Jan 14;53(1):101-14. [2]. Kong J, et al. YC-1 enhances the anti-tumor activity of sorafenib through inhibition of signal transducer and activator of transcription 3 (STAT3) in hepatocellular carcinoma. Mol Cancer. 2014 Jan 13;13:7. [3]. Chang LC, et al. YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK. Br J Pharmacol. 2014 Sep;171(17):4010-25. [4]. Komsuoglu Celikyurt I, et al. Effects of YC-1 on Learning and Memory Functions of Aged Rats. Med Sci Monit Basic Res. 2014 Aug 21;20:130-7.

Target

Kd: 0.6-1.1 μM (sGC, in the presence of CO)[1]

Additional Information

[1]. Purohit R, et al. YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. Biochemistry. 2014 Jan 14;53(1):101-14. [2]. Kong J, et al. YC-1 enhances the anti-tumor activity of sorafenib through inhibition of signal transducer and activator of transcription 3 (STAT3) in hepatocellular carcinoma. Mol Cancer. 2014 Jan 13;13:7. [3]. Chang LC, et al. YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK. Br J Pharmacol. 2014 Sep;171(17):4010-25. [4]. Komsuoglu Celikyurt I, et al. Effects of YC-1 on Learning and Memory Functions of Aged Rats. Med Sci Monit Basic Res. 2014 Aug 21;20:130-7.

Frequently Asked Questions

What is the CAS number of Lificiguat?

The CAS number of Lificiguat is 170632-47-0.

What are the molecular formula and molecular weight of Lificiguat?

Lificiguat has molecular formula C19H16N2O2 and molecular weight 304.342 g/mol.

What are the upstream and downstream products of Lificiguat?

For Lificiguat, Upstream Products: Methyl 2-furoate, 1H-Indazole, 1-Benzyl-3-iodo-1H-indazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Lificiguat (CAS 170632-47-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-27364-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.