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Amitriptyline

Also known as: 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, 10,11-Dihydro-5-(γ-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene, 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene, 5-(γ-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene, Elavil, Tryptizol, Saroten, Laroxyl, Lentizol, Amineurin, Domical, Sarotex, Triptanol, Triptilin, Proheptadiene, Sylvemid, Miketorin, Damitriptyline, Damilen, Amytriptiline

Amitriptyline (CAS 50-48-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H23N and a molecular weight of 277.40 g/mol. Key properties include a melting point of 196-197°C, a boiling point of 398.2±21.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 174.0±18.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
50-48-6
Jingsj CID
J-25098-6
Molecular Formula
C20H23N
Molecular Weight
277.40 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point196-197°C
Boiling Point398.2±21.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point174.0±18.9 °C
Exact Mass277.183044
PSA3.24000
LogP4.92
Vapor Pressure0.0±0.9 mmHg at 25°C
Refractive Index1.628
Additional Property9.7 mg/mL

Activity & Biological Data

Additional Information[1]. BrueckleMS, et al. Amitriptyline's anticholinergic adverse drug reactions-A systematicmultiple-indication review and meta-analysis. PLoS One. 2023 Apr5;18(4):e0284168.

Customs & Trade Information

HS Code2921499090
Summary2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Amitriptyline?

The CAS number of Amitriptyline is 50-48-6.

What are the molecular formula and molecular weight of Amitriptyline?

Amitriptyline has molecular formula C20H23N and molecular weight 277.40 g/mol.

What are the upstream and downstream products of Amitriptyline?

For Amitriptyline, Upstream Products: 5-(3-dimethylaminopropyl)-10,11-dihydrodibenzo[a,d]cyclohepten-5-ol, Carbon dioxide, Nortriptyline; Downstream Products: 11-prop-2-enylidene-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulene, Nortriptyline, (E)-10-Hydroxy amitriptyline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Amitriptyline (CAS 50-48-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25098-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.