Guvacine
Also known as: 1,2,5,6-Tetrahydropyridine-3-carboxylic acid, 1,2,5,6-Tetrahydronicotinic acid, 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-
Guvacine (CAS 498-96-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C6H9NO2 and a molecular weight of 127.141 g/mol. Key properties include a melting point of 306 - 309 °C(lit.), a boiling point of 280.8±35.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 123.6±25.9 °C. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.
- CAS No.
- 498-96-4
- Jingsj CID
- J-24953-6
- Molecular Formula
- C6H9NO2
- Molecular Weight
- 127.141 g/mol
- Category
- Organic Bases
- Last updated
- 11/2/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 306 - 309 °C(lit.) |
|---|---|
| Boiling Point | 280.8±35.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 123.6±25.9 °C |
| Exact Mass | 127.063332 |
| PSA | 49.33000 |
| LogP | 0.72 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.518 |
Activity & Biological Data
| Target | IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1] |
|---|---|
| Additional Information | [1]. L A Borden, et al. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol. 1994 Oct 14;269(2):219-24. |
Frequently Asked Questions
What is the CAS number of Guvacine?
The CAS number of Guvacine is 498-96-4.
What are the molecular formula and molecular weight of Guvacine?
Guvacine has molecular formula C6H9NO2 and molecular weight 127.141 g/mol.
What are the upstream and downstream products of Guvacine?
For Guvacine, Upstream Products: Diethyl 3,3'-Iminodipropionate, Methyl 1,2,5,6-tetrahydropyridine-3-carboxylate, Arecoline hydrobromide; Downstream Products: Nipecotic acid, 3-Methylpyridine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Guvacine (CAS 498-96-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-24953-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.