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3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride

Also known as: Hoffer's chlorosugar, Hoffer's alpha-chlorosugar, 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate), 1-Chloro-2-deoxy-3,5-di-O-toluoyl-α-D-ribofuranose, 1-Chloro-3,5-di-O-(p-toluoyl)-2-deoxy-α-D-ribofuranose, 3,5-Bis(toluoyl)-2-deoxyribosyl chloride, alpha-D-erythro-Pentofuranosyl chloride, 2-deoxy-, 3,5-bis(4-methylbenzoate), NSC 148837, MFCD00079148

3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride (CAS 4330-21-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C21H21ClO5 and a molecular weight of 388.84700 g/mol. Key properties include a boiling point of 467.3±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 158.9±28.8 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
4330-21-6
Jingsj CID
J-24366-3
Molecular Formula
C21H21ClO5
Molecular Weight
388.84700 g/mol
Category
Pharma Intermediates
Last updated
11/2/2026

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Physicochemical Properties

Boiling Point467.3±45.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point158.9±28.8 °C
Exact Mass332.117920
PSA27.69000
LogP4.39
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.578

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of 3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride?

The CAS number of 3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride is 4330-21-6.

What are the molecular formula and molecular weight of 3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride?

3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride has molecular formula C21H21ClO5 and molecular weight 388.84700 g/mol.

Is 3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride hazardous?

3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of 3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride?

For 3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride, Upstream Products: methyl 2-deoxy-3,5-di-O-p-toluoyl-D-ribofuranoside, 4-Methylbenzoyl chloride, 4-Methylbenzoic anhydride; Downstream Products: Cladribine, 7-Deaza-2'-deoxyadenosine, 2-Deoxy-D-ribono-1,4-lactone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3,5-Di-O-(p-toluyl)-2-deoxy-α-D-ribofuranosyl chloride (CAS 4330-21-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-24366-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.