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4-Trifluoromethylsalicylic acid

Also known as: 2-Hydroxy-4-(trifluoromethyl)benzoic acid, 4-(Trifluoromethyl)salicylic acid, p-Trifluoromethylsalicylic acid, Triflusal impurity B, Benzoic acid, 2-hydroxy-4-(trifluoromethyl)-, 4-Carboxy-3-hydroxybenzotrifluoride

4-Trifluoromethylsalicylic acid (CAS 328-90-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H5F3O3 and a molecular weight of 206.119 g/mol. Key properties include a melting point of 178ºC, a boiling point of 286.4±40.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 127.0±27.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
328-90-5
Jingsj CID
J-21609-1
Molecular Formula
C8H5F3O3
Molecular Weight
206.119 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point178ºC
Boiling Point286.4±40.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point127.0±27.3 °C
Exact Mass206.019073
PSA57.53000
LogP4.16
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.510

Activity & Biological Data

Additional Information[1]. Rodríguez G, et al. Hydrophilic polymer drug from a derivative of salicylic acid: synthesis, controlled release studies and biological behavior. Macromol Biosci. 2004;4(6):579-586.

Customs & Trade Information

HS Code2918290000
SummaryHS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4-Trifluoromethylsalicylic acid?

The CAS number of 4-Trifluoromethylsalicylic acid is 328-90-5.

What are the molecular formula and molecular weight of 4-Trifluoromethylsalicylic acid?

4-Trifluoromethylsalicylic acid has molecular formula C8H5F3O3 and molecular weight 206.119 g/mol.

What are the upstream and downstream products of 4-Trifluoromethylsalicylic acid?

For 4-Trifluoromethylsalicylic acid, Upstream Products: 4-(Trifluoromethyl)benzoic acid, Carbon dioxide, 3-(Trifluoromethyl)phenol; Downstream Products: Triflusal, Methyl 2-methoxy-4-(trifluoromethyl)benzoate, 2-Hydroxy-4-(methoxycarbonyl)benzoic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Trifluoromethylsalicylic acid (CAS 328-90-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-21609-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.