4'-chloro-2,2,2-trifluoroacetophenone
Also known as: 1-(4-chlorophenyl)-2,2,2-trifluoroethanone, 1-(4-chlorophenyl)-2,2,2-trifluoroethan-1-one, 4-chloro-alpha,alpha,alpha-trifluoroacetophenone, 4-chlorophenyl trifluoromethyl ketone, p-chloro-alpha,alpha,alpha-trifluoroacetophenone, OMEGA,OMEGA,OMEGA-TRIFLUORO-P-CHLORO ACETOPHENONE, Ethanone, 1-(4-chlorophenyl)-2,2,2-trifluoro-
4'-chloro-2,2,2-trifluoroacetophenone (CAS 321-37-9) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C8H4ClF3O and a molecular weight of 208.56500 g/mol. Key properties include a melting point of 24-26 °C(lit.), a boiling point of 180-183 °C(lit.), a density of 1.398 g/mL at 25 °C(lit.) and a flash point of 78.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.
- CAS No.
- 321-37-9
- Jingsj CID
- J-18089-2
- Molecular Formula
- C8H4ClF3O
- Molecular Weight
- 208.56500 g/mol
- Category
- Ketones
- Last updated
- 11/2/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 24-26 °C(lit.) |
|---|---|
| Boiling Point | 180-183 °C(lit.) |
| Density | 1.398 g/mL at 25 °C(lit.) |
| Flash Point | 78.9 °C |
| Exact Mass | 207.99000 |
| PSA | 17.07000 |
| LogP | 3.08500 |
| Refractive Index | n20/D 1.489(lit.) |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Customs & Trade Information
| HS Code | 2914700090 |
|---|---|
| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of 4'-chloro-2,2,2-trifluoroacetophenone?
The CAS number of 4'-chloro-2,2,2-trifluoroacetophenone is 321-37-9.
What are the molecular formula and molecular weight of 4'-chloro-2,2,2-trifluoroacetophenone?
4'-chloro-2,2,2-trifluoroacetophenone has molecular formula C8H4ClF3O and molecular weight 208.56500 g/mol.
Is 4'-chloro-2,2,2-trifluoroacetophenone hazardous?
4'-chloro-2,2,2-trifluoroacetophenone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "4'-chloro-2,2,2-trifluoroacetophenone (CAS 321-37-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18089-2 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.