Phenylephrine

Also known as: (R)-(-)-Phenylephrine, Adrianol, Isophrin, Mesaton, Mesatone, Mezaton, Mydfrin, Neophryn, Nostril, Prefrin

Phenylephrine (CAS 59-42-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C9H13NO2 and a molecular weight of 167.20500 g/mol. Key properties include a melting point of 171°C, a boiling point of 341.1ºC at 760 mmHg, a density of 1.159 g/cm3 and a flash point of 163.4ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 59-42-7
Jingsj CID: J-20254-0
Molecular Formula: C₉H₁₃NO₂
Molecular Weight: 167.20500 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	171°C
Boiling Point	341.1ºC at 760 mmHg
Density	1.159 g/cm3
Flash Point	163.4ºC
Exact Mass	167.09500
PSA	52.49000
LogP	1.03590
Refractive Index	-55.5 ° (C=5, 1mol/L HCl)

Activity & Biological Data

Additional Information	[1]. Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121(6):1127-35. [2]. Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46(5):929-36. [3]. Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13. [4]. Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 ( Pt 2):459-65. [5]. Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28(1):1-6.

Additional Information

[1]. Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121(6):1127-35. [2]. Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46(5):929-36. [3]. Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13. [4]. Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 ( Pt 2):459-65. [5]. Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28(1):1-6.

Frequently Asked Questions

What is the CAS number of Phenylephrine?

The CAS number of Phenylephrine is 59-42-7.

What are the molecular formula and molecular weight of Phenylephrine?

Phenylephrine has molecular formula C9H13NO2 and molecular weight 167.20500 g/mol.

What are the upstream and downstream products of Phenylephrine?

For Phenylephrine, Upstream Products: 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride, m-Anisaldehyde; Downstream Products: (R)-5-(3-Hydroxyphenyl)-3-methyl-2-oxazolidinone, Phenylephrine hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Phenylephrine (CAS 59-42-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-20254-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.