2-Methoxyestradiol
Also known as: 2-Methoxy-17β-estradiol, 2-Methoxy-β-estradiol, 2-MeO-E2, 2-Methoxyestra-1,3,5(10)-triene-3,17β-diol, 2-Methoxy-17b-estradiol, 2-Methoxy-β-estradiol, Panzem, NSC 659853, 2-Hydroxyestradiol 2-methyl ether, 2-Methoxy-oestradiol
2-Methoxyestradiol (CAS 362-07-2) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C19H26O3 and a molecular weight of 302.408 g/mol. Key properties include a melting point of 188-190°C, a boiling point of 464.4±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 234.7±28.7 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H311 — Toxic in contact with skin and H331 — Toxic if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 362-07-2
- Jingsj CID
- J-20198-9
- Molecular Formula
- C19H26O3
- Molecular Weight
- 302.408 g/mol
- Category
- Alcohols
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 188-190°C |
|---|---|
| Boiling Point | 464.4±45.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 234.7±28.7 °C |
| Exact Mass | 302.188202 |
| PSA | 49.69000 |
| LogP | 3.84 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.586 |
| Additional Property | DMSO: 10 mg/mL |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H311 — Toxic in contact with skin
- H331 — Toxic if inhaled
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
- H350 — May cause cancer
- H360 — May damage fertility or the unborn child
- H372 — Causes damage to organs through prolonged exposure
- H410 — Very toxic to aquatic life with long lasting effects
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Kamath K, et al. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Mol Cancer Ther. 2006 Sep;5(9):2225-33. [2]. Aquino-Gálvez A, et al. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia. Oncol Rep. 2016 Jan;35(1):577-83. [3]. Xu L, et al. 2-Methoxyestradiol Alleviates Experimental Autoimmune Uveitis by Inhibiting Lymphocytes Proliferation and T Cell Differentiation. Biomed Res Int. 2016;2016:7948345. [4]. Kang SH, et al. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Res. 2006, 66(24),11991-11997. |
Frequently Asked Questions
What is the CAS number of 2-Methoxyestradiol?
The CAS number of 2-Methoxyestradiol is 362-07-2.
What are the molecular formula and molecular weight of 2-Methoxyestradiol?
2-Methoxyestradiol has molecular formula C19H26O3 and molecular weight 302.408 g/mol.
Is 2-Methoxyestradiol hazardous?
2-Methoxyestradiol has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H311 — Toxic in contact with skin; H331 — Toxic if inhaled.
What are the upstream and downstream products of 2-Methoxyestradiol?
For 2-Methoxyestradiol, Upstream Products: 2-Methoxyestrone, Sodium methoxide, Estra-1,3,5(10)-triene-3,17-diol, 2-bromo-, (17β)-; Downstream Products: 2-Hydroxyestradiol, 2-Methoxyestrone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Methoxyestradiol (CAS 362-07-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-20198-9 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.