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2-Methoxy-3-(trifluoromethyl)pyridine

Also known as: 2-Methoxy-3-(trifluoromethyl)pyridine, 2-Methoxy-3-trifluoromethylpyridine, 3-(trifluoromethyl)-2-methoxypyridine, MFCD00153202, Pyridine, 2-methoxy-3-(trifluoromethyl)-

2-Methoxy-3-(trifluoromethyl)pyridine (CAS 121643-44-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H6F3NO and a molecular weight of 177.124 g/mol. Key properties include a boiling point of 172.9±40.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 58.4±27.3 °C. It is classified under GHS with signal word Danger and hazard statements H226 — Flammable liquid and vapour, H300 and H315 — Causes skin irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
121643-44-5
Jingsj CID
J-1993895-5
Molecular Formula
C7H6F3NO
Molecular Weight
177.124 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026
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Physicochemical Properties

Boiling Point172.9±40.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point58.4±27.3 °C
Exact Mass177.040146
PSA22.12000
LogP2.76
Vapor Pressure1.7±0.3 mmHg at 25°C
Refractive Index1.427

GHS Safety & Compliance

Flammable / Acute ToxicitySignal word: Danger
  • H226 — Flammable liquid and vapour
  • H300
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of 2-Methoxy-3-(trifluoromethyl)pyridine?

The CAS number of 2-Methoxy-3-(trifluoromethyl)pyridine is 121643-44-5.

What are the molecular formula and molecular weight of 2-Methoxy-3-(trifluoromethyl)pyridine?

2-Methoxy-3-(trifluoromethyl)pyridine has molecular formula C7H6F3NO and molecular weight 177.124 g/mol.

Is 2-Methoxy-3-(trifluoromethyl)pyridine hazardous?

2-Methoxy-3-(trifluoromethyl)pyridine has GHS signal word Danger and hazard statements H226 — Flammable liquid and vapour; H300; H315 — Causes skin irritation.

What are the upstream and downstream products of 2-Methoxy-3-(trifluoromethyl)pyridine?

For 2-Methoxy-3-(trifluoromethyl)pyridine, Upstream Products: Sodium methoxide, 2-Chloro-3-(trifluoromethyl)pyridine, Sodium trifluoromethanesulfinate; Downstream Products: 5-bromo-2-methoxy-3-(trifluoromethyl)pyridine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Methoxy-3-(trifluoromethyl)pyridine (CAS 121643-44-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1993895-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.