2-Chloro-3-(trifluoromethyl)pyridine

Also known as: 2-Chloro-3-(trifluoromethyl)pyridine, 6-chloro-5-trifluoromethylpyridine, 2-Chloro-alpha,alpha,alpha-trifluoro-3-picoline, 2-Chloro-3-trifluoromethylpyridine, Pyridine, 2-chloro-3-(trifluoromethyl)-, MFCD00042223, EINECS 424-520-6

2-Chloro-3-(trifluoromethyl)pyridine (CAS 65753-47-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H3ClF3N and a molecular weight of 181.543 g/mol. Key properties include a melting point of 36-40 °C(lit.), a boiling point of 181.7±35.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 63.7±25.9 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H311 — Toxic in contact with skin and H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 65753-47-1
Jingsj CID: J-1135637-9
Molecular Formula: C₆H₃ClF₃N
Molecular Weight: 181.543 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	36-40 °C(lit.)
Boiling Point	181.7±35.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	63.7±25.9 °C
Exact Mass	180.990616
PSA	12.89000
LogP	2.51
Vapor Pressure	1.1±0.3 mmHg at 25°C
Refractive Index	1.447

GHS Safety & Compliance

Corrosion / Acute Toxicity / Health HazardSignal word: Danger

H301 — Toxic if swallowed
H311 — Toxic in contact with skin
H314 — Causes severe skin burns and eye damage
H372 — Causes damage to organs through prolonged exposure
H412 — Harmful to aquatic life with long lasting effects

Customs & Trade Information

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Chloro-3-(trifluoromethyl)pyridine?

The CAS number of 2-Chloro-3-(trifluoromethyl)pyridine is 65753-47-1.

What are the molecular formula and molecular weight of 2-Chloro-3-(trifluoromethyl)pyridine?

2-Chloro-3-(trifluoromethyl)pyridine has molecular formula C6H3ClF3N and molecular weight 181.543 g/mol.

Is 2-Chloro-3-(trifluoromethyl)pyridine hazardous?

2-Chloro-3-(trifluoromethyl)pyridine has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H311 — Toxic in contact with skin; H314 — Causes severe skin burns and eye damage.

What are the upstream and downstream products of 2-Chloro-3-(trifluoromethyl)pyridine?

For 2-Chloro-3-(trifluoromethyl)pyridine, Upstream Products: 3-(Trifluoromethyl)pyridine 1-oxide, Trimethyl(trifluoromethyl)silane, 2-Chloro-3-iodopyridine; Downstream Products: 3-(Trifluoromethyl)-2-pyridinecarbonitrile, 3-(Trifluoromethyl)pyridine, Bibenzyl.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2-Chloro-3-(trifluoromethyl)pyridine (CAS 65753-47-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1135637-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.