7-Hydroxy-4-(trifluoromethyl)coumarin
Also known as: 2H-1-Benzopyran-2-one, 7-hydroxy-4-(trifluoromethyl)-, 4-(Trifluoromethyl)umbelliferone, 7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one, 7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one, 7-hydroxy-4-(trifluoromethyl)chromen-2-one, TFMU, MFCD00037578, 4-(TRIFLUOROMETHYL)UMBELLIFERONE
7-Hydroxy-4-(trifluoromethyl)coumarin (CAS 575-03-1) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C10H5F3O3 and a molecular weight of 230.140 g/mol. Key properties include a melting point of 178-180 °C(lit.), a boiling point of 311.4±42.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 142.2±27.9 °C. It is classified under GHS with signal word Danger and hazard statements H300, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 575-03-1
- Jingsj CID
- J-1991492-5
- Molecular Formula
- C10H5F3O3
- Molecular Weight
- 230.140 g/mol
- Category
- Organohalogen Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 178-180 °C(lit.) |
|---|---|
| Boiling Point | 311.4±42.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 142.2±27.9 °C |
| Exact Mass | 230.019073 |
| PSA | 50.44000 |
| LogP | 2.88 |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| Refractive Index | 1.546 |
| Additional Property | DMF: soluble |
GHS Safety & Compliance
- H300
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31(12):861-78. |
|---|
Customs & Trade Information
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 7-Hydroxy-4-(trifluoromethyl)coumarin?
The CAS number of 7-Hydroxy-4-(trifluoromethyl)coumarin is 575-03-1.
What are the molecular formula and molecular weight of 7-Hydroxy-4-(trifluoromethyl)coumarin?
7-Hydroxy-4-(trifluoromethyl)coumarin has molecular formula C10H5F3O3 and molecular weight 230.140 g/mol.
Is 7-Hydroxy-4-(trifluoromethyl)coumarin hazardous?
7-Hydroxy-4-(trifluoromethyl)coumarin has GHS signal word Danger and hazard statements H300; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of 7-Hydroxy-4-(trifluoromethyl)coumarin?
For 7-Hydroxy-4-(trifluoromethyl)coumarin, Upstream Products: Ethyl 4,4,4-trifluoroacetoacetate, Resorcinol, Ethyl 5,5,5-trifluoro-4-oxopentanoate; Downstream Products: 7-Methoxy-4-(trifluoromethyl)coumarin.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "7-Hydroxy-4-(trifluoromethyl)coumarin (CAS 575-03-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1991492-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.