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Ethyl 4,4,4-trifluoroacetoacetate

Also known as: ETFAA, Ethyl trifluoroacetoacetate, Ethyl 4,4,4-trifluoro-3-oxobutanoate, Ethyl 4,4,4-trifluoro-3-oxobutyrate, 4,4,4-Trifluoroacetoacetic acid ethyl ester, Ethyl 3-oxo-4,4,4-trifluorobutanoate, Ethyl (trifluoroacetyl)acetate, Ethyl 4,4,4-trifluoroacetoacetate, 1-Ethoxy-4,4,4-trifluorobutane-1,3-dione, Acetoacetic acid, 4,4,4-trifluoro-, ethyl ester, Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester, Ethyl 4,4,4-trifluoro-3-ketobutyrate, Ethyl 3-trifluoromethyl-3-oxopropionate, Ethyl 3-trifluoromethyl-3-oxopropanoate

Ethyl 4,4,4-trifluoroacetoacetate (CAS 372-31-6) is a compound in the Solvents category listed in the Jingsj chemical database. It has the molecular formula C6H7F3O3 and a molecular weight of 184.113 g/mol. Key properties include a melting point of -39 °C, a boiling point of 129.5±0.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 28.9±0.0 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour, H302 — Harmful if swallowed and H412 — Harmful to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
372-31-6
Jingsj CID
J-44766-7
Molecular Formula
C6H7F3O3
Molecular Weight
184.113 g/mol
Category
Solvents
Last updated
8/21/2026

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Physicochemical Properties

Melting Point-39 °C
Boiling Point129.5±0.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point28.9±0.0 °C
Exact Mass184.034729
PSA43.37000
LogP2.47
Vapor Pressure10.1±0.2 mmHg at 25°C
Refractive Index1.363
Storage ConditionsFlammables area
Additional Property10 g/L (20 ºC)

GHS Safety & Compliance

Flammable / IrritantSignal word: Warning
  • H226 — Flammable liquid and vapour
  • H302 — Harmful if swallowed
  • H412 — Harmful to aquatic life with long lasting effects

Customs & Trade Information

HS Code2918300090
Summary2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Ethyl 4,4,4-trifluoroacetoacetate?

The CAS number of Ethyl 4,4,4-trifluoroacetoacetate is 372-31-6.

What are the molecular formula and molecular weight of Ethyl 4,4,4-trifluoroacetoacetate?

Ethyl 4,4,4-trifluoroacetoacetate has molecular formula C6H7F3O3 and molecular weight 184.113 g/mol.

Is Ethyl 4,4,4-trifluoroacetoacetate hazardous?

Ethyl 4,4,4-trifluoroacetoacetate has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H302 — Harmful if swallowed; H412 — Harmful to aquatic life with long lasting effects.

What are the upstream and downstream products of Ethyl 4,4,4-trifluoroacetoacetate?

For Ethyl 4,4,4-trifluoroacetoacetate, Upstream Products: Ethyl trifluoroacetate, Ethyl acetate, Triethyl phosphonoacetate; Downstream Products: 4,4,4-Trifluoro-2-propyl-3-oxobutyric acid ethyl ester, 1-Phenyl-3-(trifluoromethyl)-2-pyrazolin-5-one, 6-fluoro-4-(trifluoromethyl)quinolin-2(1H)-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Ethyl 4,4,4-trifluoroacetoacetate (CAS 372-31-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44766-7 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.