Naquotinib

Also known as: (R)-5-((1-acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide, 2-Pyrazinecarboxamide, 6-ethyl-3-[[4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[[(3R)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]oxy]-, 5-{[(3R)-1-Acryloyl-3-pyrrolidinyl]oxy}-6-ethyl-3-({4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl}amino)-2-pyrazinecarboxamide, 6-Ethyl-3-[[4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[[(3R)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]oxy]-2-pyrazinecarboxamide, 6-Ethyl-3-{4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino}-5-{[(3R)-1-(prop-2-enoyl)pyrrolidin-3-yl]oxy}pyrazine-2-carboxamide, 6-ethyl-3-({4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-5-{[(3R)-1-(1-oxoprop-2-en-1-yl)pyrrolidin-3-yl]oxy}pyrazine-2-carboxamide, ASP-8273, ASP8273, Epidermal growth factor receptor,EGFR,ASP 8273,HER1,ErbB-1,ASP-8273,inhibit,Naquotinib,Inhibitor, NAQUOTINIB (FREE BASE), Naquotinib,ASP-8273, UNII-47DD4548PB

Naquotinib (CAS 1448232-80-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C30H42N8O3 and a molecular weight of 562.706 g/mol. It is also known as (R)-5-((1-acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide, 2-Pyrazinecarboxamide, 6-ethyl-3-[[4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[[(3R)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]oxy]- and 5-{[(3R)-1-Acryloyl-3-pyrrolidinyl]oxy}-6-ethyl-3-({4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl}amino)-2-pyrazinecarboxamide. Key properties include a boiling point of 717.6±60.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 387.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1448232-80-1
Jingsj CID: J-1987922-8
Molecular Formula: C₃₀H₄₂N₈O₃
Molecular Weight: 562.706 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	717.6±60.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	387.8±32.9 °C

Frequently Asked Questions

What is the CAS number of Naquotinib?

The CAS number of Naquotinib is 1448232-80-1.

What are the molecular formula and molecular weight of Naquotinib?

Naquotinib has molecular formula C30H42N8O3 and molecular weight 562.706 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Naquotinib (CAS 1448232-80-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987922-8 (accessed 2026-10-25).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.