7-Chloro-4-(piperazin-1-yl)quinoline

Also known as: 7-Chloro-4-piperazinoquinoline, 7-Chloro-4-piperazin-1-yl-quinoline, 7-chloro-2-(1-piperazinyl)quinoline, 7-chloro-2-piperazin-1-ylquinoline, Piperaquine Impurity I, Piperaquine Impurity 6, Piperaquine Impurity A, Piperaquine Phosphate Impurity I, TIMTEC-BB SBB007478, BUTTPARK 50\09-11, Compound Fr13587

7-Chloro-4-(piperazin-1-yl)quinoline (CAS 837-52-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C13H14ClN3 and a molecular weight of 247.72300 g/mol. Key properties include a melting point of 113-116ºC, a boiling point of 433.5ºC at 760 mmHg, a density of 1.257 g/cm3 and a flash point of 216ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 837-52-5
Jingsj CID: J-1987443-2
Molecular Formula: C₁₃H₁₄ClN₃
Molecular Weight: 247.72300 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	113-116ºC
Boiling Point	433.5ºC at 760 mmHg
Density	1.257 g/cm3
Flash Point	216ºC
Exact Mass	247.08800
PSA	28.16000
LogP	2.69160
Refractive Index	1.636
Storage Conditions	2-8°C

Activity & Biological Data

Additional Information	[1]. Aida M Abd El-Sattar El-Azzouny, et al. Structural and biological survey of 7-chloro-4-(piperazin-1-yl)quinoline and its derivatives. Drug Dev Res. 2020 Nov;81(7):786-802.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 7-Chloro-4-(piperazin-1-yl)quinoline?

The CAS number of 7-Chloro-4-(piperazin-1-yl)quinoline is 837-52-5.

What are the molecular formula and molecular weight of 7-Chloro-4-(piperazin-1-yl)quinoline?

7-Chloro-4-(piperazin-1-yl)quinoline has molecular formula C13H14ClN3 and molecular weight 247.72300 g/mol.

What are the upstream and downstream products of 7-Chloro-4-(piperazin-1-yl)quinoline?

For 7-Chloro-4-(piperazin-1-yl)quinoline, Upstream Products: Piperazine, 4,7-Dichloroquinoline; Downstream Products: Piperaquine phosphate, KM11060.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "7-Chloro-4-(piperazin-1-yl)quinoline (CAS 837-52-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987443-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.