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KM11060

Also known as: KM 11060, KM-11060, 7-chloro-4-(4-(4-chlorophenylsulfonyl)piperazin-1-yl)quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]quinoline, 7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline, 7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazino}quinoline, Quinoline, 7-chloro-4-[4-[(4-chlorophenyl)sulfonyl]-1-piperazinyl]-, CFTR-F508del corrector, KM11060

KM11060 (CAS 774549-97-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C19H17Cl2N3O2S and a molecular weight of 422.328 g/mol. Key properties include a boiling point of 607.3±65.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 321.1±34.3 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
774549-97-2
Jingsj CID
J-1959959-8
Molecular Formula
C19H17Cl2N3O2S
Molecular Weight
422.328 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point607.3±65.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point321.1±34.3 °C
Exact Mass421.041840
PSA61.89000
LogP4.19
Vapor Pressure0.0±1.7 mmHg at 25°C
Refractive Index1.676
Storage Conditions2-8℃

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H301 — Toxic if swallowed

Activity & Biological Data

Additional Information[1]. Robert R, et al. Structural analog of sildenafil identified as a novel corrector of the F508del-CFTR trafficking defect. Mol Pharmacol. 2008 Feb;73(2):478-89. [2]. Wu H, et al. Lipoxin A4 and platelet activating factor are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice. PLoS One. 2014 Mar 26;9(3):e93003.

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of KM11060?

The CAS number of KM11060 is 774549-97-2.

What are the molecular formula and molecular weight of KM11060?

KM11060 has molecular formula C19H17Cl2N3O2S and molecular weight 422.328 g/mol.

Is KM11060 hazardous?

KM11060 has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

What are the upstream and downstream products of KM11060?

For KM11060, Upstream Products: 4-Chlorobenzenesulfonyl chloride, 7-Chloro-4-(piperazin-1-yl)quinoline, 4,7-Dichloroquinoline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "KM11060 (CAS 774549-97-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959959-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.