Cetirizine dihydrochloride
Also known as: Cetirizine hydrochloride, Cetirizine HCl, Cetirizine 2HCl, 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride, Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2), (2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid dihydrochloride, Zyrtec, Reactine, Virlix, Zyrlex, Alercet, Alerid, Cesta, Cetiriz, Cetrak, Cetrizet, Zirtek, MFCD00941428
Cetirizine dihydrochloride (CAS 83881-52-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C21H27Cl3N2O3 and a molecular weight of 461.81 g/mol. Key properties include a melting point of 110-115ºC, a boiling point of 542.1ºC at 760 mmHg, a density of 1.237 g/cm3 and a flash point of 281.6ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 83881-52-1
- Jingsj CID
- J-1986816-7
- Molecular Formula
- C21H27Cl3N2O3
- Molecular Weight
- 461.81 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 110-115ºC |
|---|---|
| Boiling Point | 542.1ºC at 760 mmHg |
| Density | 1.237 g/cm3 |
| Flash Point | 281.6ºC |
| PSA | 53.01000 |
| LogP | 3.82600 |
| Storage Conditions | Desiccate at RT |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Additional Information | [1]. Naclerio RM. Additional properties of cetirizine, a new H1 antagonist. Allergy Proc. 1991 May-Jun;12(3):187-91. [2]. Meh A, et al. Effect of cetirizine, a histamine (H(1)) receptor antagonist, on bone modeling during orthodontic tooth movement in rats. Am J Orthod Dentofacial Orthop. 2011 Apr;139(4):e323-9. |
|---|
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Cetirizine dihydrochloride?
The CAS number of Cetirizine dihydrochloride is 83881-52-1.
What are the molecular formula and molecular weight of Cetirizine dihydrochloride?
Cetirizine dihydrochloride has molecular formula C21H27Cl3N2O3 and molecular weight 461.81 g/mol.
Is Cetirizine dihydrochloride hazardous?
Cetirizine dihydrochloride has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Cetirizine dihydrochloride?
For Cetirizine dihydrochloride, Upstream Products: Cetirizine, 2-[4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl]ethanol, Sodium chloroacetate; Downstream Products: Cetirizine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Cetirizine dihydrochloride (CAS 83881-52-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986816-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.