Bardoxolone methyl
Also known as: Bardoxolone methyl ester, CDDO Methyl ester, 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester, Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate, NSC 713200, RTA 402, TP-155
Bardoxolone methyl (CAS 218600-53-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C32H43NO4 and a molecular weight of 505.688 g/mol. Key properties include a melting point of 215-223 °C, a boiling point of 600.8±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 256.5±21.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 218600-53-4
- Jingsj CID
- J-1986485-8
- Molecular Formula
- C32H43NO4
- Molecular Weight
- 505.688 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 215-223 °C |
|---|---|
| Boiling Point | 600.8±55.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 256.5±21.7 °C |
| Exact Mass | 505.319214 |
| PSA | 84.23000 |
| LogP | 6.22 |
| Vapor Pressure | 0.0±1.7 mmHg at 25°C |
| Refractive Index | 1.559 |
| Storage Conditions | -20 °C |
Activity & Biological Data
| Target | Nrf2[1] |
|---|---|
| Additional Information | [1]. Reisman SA, et al. Bardoxolone Methyl Decreases Megalin and Activates Nrf2 in the Kidney. J Am Soc Nephrol. 2012 Aug 2. [2]. McCullough PA, et al. Cardiac and renal function in patients with type 2 diabetes who have chronic kidney disease: potential effects of bardoxolone methyl. Drug Des Devel Ther. 2012;6:141-9. |
Customs & Trade Information
| HS Code | 2926909090 |
|---|---|
| Summary | HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Bardoxolone methyl?
The CAS number of Bardoxolone methyl is 218600-53-4.
What are the molecular formula and molecular weight of Bardoxolone methyl?
Bardoxolone methyl has molecular formula C32H43NO4 and molecular weight 505.688 g/mol.
What are the upstream and downstream products of Bardoxolone methyl?
For Bardoxolone methyl, Upstream Products: Oleanolic acid, Methyl oleanolate, Methyl 3,12-dioxoolean-9(11)-en-28-oate; Downstream Products: Bardoxolone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Bardoxolone methyl (CAS 218600-53-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1986485-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.