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Clodronate disodium

Also known as: Dichloromethylenediphosphonic acid disodium salt, Clodronic acid disodium salt, Disodium clodronate, Cl2MDP, DMDP, Sodium clodronate, Disodium (dichloromethylene)bis[hydrogen (phosphonate)], Bonefos, Loron, Ostac, Mebonat

Clodronate disodium (CAS 22560-50-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula CH2Cl2Na2O6P2 and a molecular weight of 288.856 g/mol. Key properties include a melting point of >330ºC, a boiling point of 474.7ºC at 760mmHg, a density of 2.306g/cm3 and a flash point of 240.9ºC. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.
22560-50-5
Jingsj CID
J-1985008-1
Molecular Formula
CH2Cl2Na2O6P2
Molecular Weight
288.856 g/mol
Category
Organic Acids
Last updated
11/3/2026

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Physicochemical Properties

Melting Point>330ºC
Boiling Point474.7ºC at 760mmHg
Density2.306g/cm3
Flash Point240.9ºC
Exact Mass287.849915
PSA140.34000
LogP1.30710
Vapor Pressure2.55E-10mmHg at 25°C
Storage Conditions-20°C Freezer

Activity & Biological Data

Additional Information[1]. Mönkkönen J, et al. Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by RAW 264 cells. Life Sci. 1994;54(14):PL229‐PL234. [2]. Tanakol R, et al. Clodronic acid in the treatment of postmenopausal osteoporosis. Clin Drug Investig. 2007;27(6):419‐433. [3]. Itoh F, et al. Effects of clodronate and alendronate on local and systemic changes in bone metabolism in rats with adjuvant arthritis. Inflammation. 2004;28(1):15‐21.

Customs & Trade Information

HS Code2931900090
Summary2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Clodronate disodium?

The CAS number of Clodronate disodium is 22560-50-5.

What are the molecular formula and molecular weight of Clodronate disodium?

Clodronate disodium has molecular formula CH2Cl2Na2O6P2 and molecular weight 288.856 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Clodronate disodium (CAS 22560-50-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1985008-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.