OSI-930
Also known as: 3-(Quinolin-4-ylmethylamino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide, 3-[(4-Quinolinylmethyl)amino]-N-[4-(trifluoromethoxy)phenyl]-2-thiophenecarboxamide, CS-1804, N-(4-trifluoromethoxyphenyl) 3-[(quinolin-4-ylmethyl)amino]thiophene-2-carboxamide, OSI 930, OSI-930 USP/EP/BP, OSI930, Thiophenib
OSI-930 (CAS 728033-96-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C22H16F3N3O2S and a molecular weight of 443.441 g/mol. Key properties include a boiling point of 517.4±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 266.7±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 728033-96-3
- Jingsj CID
- J-1982289-9
- Molecular Formula
- C22H16F3N3O2S
- Molecular Weight
- 443.441 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 517.4±50.0 °C at 760 mmHg |
|---|---|
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 266.7±30.1 °C |
| Exact Mass | 443.091522 |
| PSA | 91.49000 |
| LogP | 5.10 |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| Refractive Index | 1.687 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Additional Information | [1]. Garton AJ, et al. OSI-930: a novel selective inhibitor of Kit and kinase insert domain receptor tyrosine kinases with antitumor activity in mouse xenograft models. Cancer Res. 2006, 66(2):1015-1024. [2]. Lin HL, et al. Inactivation of cytochrome P450 (P450) 3A4 but not P450 3A5 by OSI-930, a thiophene-containing anticancer drug. Drug Metab Dispos. 2011, 39(2), 345-350. |
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Frequently Asked Questions
What is the CAS number of OSI-930?
The CAS number of OSI-930 is 728033-96-3.
What are the molecular formula and molecular weight of OSI-930?
OSI-930 has molecular formula C22H16F3N3O2S and molecular weight 443.441 g/mol.
What are the upstream and downstream products of OSI-930?
For OSI-930, Upstream Products: Quinoline-4-carbaldehyde.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "OSI-930 (CAS 728033-96-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1982289-9 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.