4'-Hydroxydiclofenac

Also known as: 2-((2,6-Dichloro-4-hydroxyphenyl)amino)benzeneacetic acid, 2-[2-(2,6-dichloro-4-hydroxyanilino)phenyl]acetic acid, 4'-OHD, 4'-Hydroxy Diclofenac, 4-Hydroxy diclofenac, Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)amino]-, Diclofenac, 4'-hydroxy-, {2-[(2,6-Dichloro-4-hydroxyphenyl)amino]phenyl}acetic acid

4'-Hydroxydiclofenac (CAS 64118-84-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H11Cl2NO3 and a molecular weight of 312.148 g/mol. Key properties include a melting point of 178-185ºC dec., a boiling point of 432.7±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 215.5±28.7 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H302 — Harmful if swallowed and H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 64118-84-9
Jingsj CID: J-1981663-8
Molecular Formula: C₁₄H₁₁Cl₂NO₃
Molecular Weight: 312.148 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	178-185ºC dec.
Boiling Point	432.7±45.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	215.5±28.7 °C
Exact Mass	311.011597
PSA	69.56000
LogP	4.56
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.690
Storage Conditions	−20°C
Additional Property	Soluble in DMSO, ethanol or methanol

GHS Safety & Compliance

Flammable / IrritantSignal word: Danger

H225 — Highly flammable liquid and vapour
H302 — Harmful if swallowed
H312 — Harmful in contact with skin
H332 — Harmful if inhaled
H319 — Causes serious eye irritation

Activity & Biological Data

Additional Information	[1]. J Shimamoto, et al. Lack of Differences in Diclofenac (A Substrate for CYP2C9) Pharmacokinetics in Healthy Volunteers With Respect to the Single CYP2C9*3 Allele. Eur J Clin Pharmacol. 2000 Apr;56(1):65-8. [2]. Hidetaka Kamimura, et al. Formation of the Accumulative Human Metabolite and Human-Specific Glutathione Conjugate of Diclofenac in TK-NOG Chimeric Mice With Humanized Livers. Drug Metab Dispos. 2015 Mar;43(3):309-16.

Additional Information

[1]. J Shimamoto, et al. Lack of Differences in Diclofenac (A Substrate for CYP2C9) Pharmacokinetics in Healthy Volunteers With Respect to the Single CYP2C9*3 Allele. Eur J Clin Pharmacol. 2000 Apr;56(1):65-8. [2]. Hidetaka Kamimura, et al. Formation of the Accumulative Human Metabolite and Human-Specific Glutathione Conjugate of Diclofenac in TK-NOG Chimeric Mice With Humanized Livers. Drug Metab Dispos. 2015 Mar;43(3):309-16.

Customs & Trade Information

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4'-Hydroxydiclofenac?

The CAS number of 4'-Hydroxydiclofenac is 64118-84-9.

What are the molecular formula and molecular weight of 4'-Hydroxydiclofenac?

4'-Hydroxydiclofenac has molecular formula C14H11Cl2NO3 and molecular weight 312.148 g/mol.

Is 4'-Hydroxydiclofenac hazardous?

4'-Hydroxydiclofenac has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H302 — Harmful if swallowed; H312 — Harmful in contact with skin.

What are the upstream and downstream products of 4'-Hydroxydiclofenac?

For 4'-Hydroxydiclofenac, Upstream Products: Diclofenac, Diclofenac sodium, 2,5-Cyclohexadiene-1,4-dione, monoxime.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4'-Hydroxydiclofenac (CAS 64118-84-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981663-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.