Diclofenac

Also known as: 2-(2,6-Dichloroanilino)phenylacetic acid, 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid, Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, N-(2,6-Dichlorophenyl)-o-aminophenylacetic acid, Diclofenac acid

Diclofenac (CAS 15307-86-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H11Cl2NO2 and a molecular weight of 296.149 g/mol. Key properties include a melting point of 156-158ºC, a boiling point of 412.0±45.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 203.0±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 15307-86-5
Jingsj CID: J-1099959-4
Molecular Formula: C₁₄H₁₁Cl₂NO₂
Molecular Weight: 296.149 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	156-158ºC
Boiling Point	412.0±45.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	203.0±28.7 °C
Exact Mass	295.016693
PSA	49.33000
LogP	4.06
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.662

Activity & Biological Data

Target	Human COX-2:1.3 nM (IC50, in CHO cells) Human COX-1:4 nM (IC50, in CHO cells) Ovine COX-2:0.84 μM (IC50) Ovine COX-1:5.1 μM (IC50)
Additional Information	[1]. Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17. [2]. Labib MB, et al. Design, synthesis of novel isoindoline hybrids as COX-2 inhibitors: Anti-inflammatory, analgesic activities and docking study. Bioorg Chem. 2018 Oct;80:70-80. [3]. Curcelli EC, et al. Beneficial effects of diclofenac therapy on serum lipids, oxidized low-density lipoprotein and antioxidant defenses in rats. Life Sci. 2008 Apr 9;82(15-16):892-8.

Target

Human COX-2:1.3 nM (IC50, in CHO cells) Human COX-1:4 nM (IC50, in CHO cells) Ovine COX-2:0.84 μM (IC50) Ovine COX-1:5.1 μM (IC50)

Additional Information

[1]. Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17. [2]. Labib MB, et al. Design, synthesis of novel isoindoline hybrids as COX-2 inhibitors: Anti-inflammatory, analgesic activities and docking study. Bioorg Chem. 2018 Oct;80:70-80. [3]. Curcelli EC, et al. Beneficial effects of diclofenac therapy on serum lipids, oxidized low-density lipoprotein and antioxidant defenses in rats. Life Sci. 2008 Apr 9;82(15-16):892-8.

Customs & Trade Information

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Diclofenac?

The CAS number of Diclofenac is 15307-86-5.

What are the molecular formula and molecular weight of Diclofenac?

Diclofenac has molecular formula C14H11Cl2NO2 and molecular weight 296.149 g/mol.

What are the upstream and downstream products of Diclofenac?

For Diclofenac, Upstream Products: Diclofenac sodium, Water, 1,2-Dichlorobenzene; Downstream Products: 5-Hydroxy Diclofenac, 4'-Hydroxydiclofenac, 1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Diclofenac (CAS 15307-86-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1099959-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.