Fingolimod

Also known as: FTY720, Gilenya, 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, Fingolimod Base, 2-amino-2-(4-octylphenethyl)propane-1,3-diol

Fingolimod (CAS 162359-55-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H33NO2 and a molecular weight of 307.471 g/mol. Key properties include a boiling point of 479.5±45.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 243.8±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 162359-55-9
Jingsj CID: J-1977877-9
Molecular Formula: C₁₉H₃₃NO₂
Molecular Weight: 307.471 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	479.5±45.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	243.8±28.7 °C
Exact Mass	307.251129
PSA	66.48000
LogP	5.25
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.531
Storage Conditions	2-8°C

Activity & Biological Data

Target	IC50: 0.033 nM (S1P, in K562 and NK cells)[1]
Additional Information	[1]. Rolin J, et al. FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. Cancer Immunol Immunother. 2010, 59(4), 575-586. [2]. Szepanowski F, et al. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling. J Neuroinflammation. 2016 Jun 10;13(1):143. [3]. Airas L, et al. In vivo PET imaging demonstrates diminished microglial activation after fingolimod treatment in an animal model of multiple sclerosis. J Nucl Med. 2015 Feb;56(2):305-10. [4]. Shirakabe K, et al. Modification of lymphocyte migration to Peyer's patches by inhibition of sphingosine-1-phosphate lyase ameliorates murine colitis. J Gastroenterol Hepatol. 2018 Jan 15.

Target

IC50: 0.033 nM (S1P, in K562 and NK cells)[1]

Additional Information

[1]. Rolin J, et al. FTY720 and SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. Cancer Immunol Immunother. 2010, 59(4), 575-586. [2]. Szepanowski F, et al. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling. J Neuroinflammation. 2016 Jun 10;13(1):143. [3]. Airas L, et al. In vivo PET imaging demonstrates diminished microglial activation after fingolimod treatment in an animal model of multiple sclerosis. J Nucl Med. 2015 Feb;56(2):305-10. [4]. Shirakabe K, et al. Modification of lymphocyte migration to Peyer's patches by inhibition of sphingosine-1-phosphate lyase ameliorates murine colitis. J Gastroenterol Hepatol. 2018 Jan 15.

Frequently Asked Questions

What is the CAS number of Fingolimod?

The CAS number of Fingolimod is 162359-55-9.

What are the molecular formula and molecular weight of Fingolimod?

Fingolimod has molecular formula C19H33NO2 and molecular weight 307.471 g/mol.

What are the upstream and downstream products of Fingolimod?

For Fingolimod, Upstream Products: 3-(Hydroxymethyl)-3-nitro-1-(4-octylphenyl)-1,4-butanediol, N-[1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide, 3-Nitro-1-(4-octylphenyl)-1-propanone; Downstream Products: FTY720 (S)-Phosphate, [1,1-Bis(hydroxymethyl)-3-(4-octylphenyl)propyl]carbamic acid phenylmethyl ester.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Fingolimod (CAS 162359-55-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1977877-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.