Kenpaullone
Also known as: 9-Bromopaullone, NSC-664704, 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one, 9-Bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one, 9-Bromo-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one, MFCD02683595
Kenpaullone (CAS 142273-20-9) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C16H11BrN2O and a molecular weight of 327.175 g/mol. Key properties include a melting point of >300ºC (dec.), a boiling point of 613.0±45.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 324.5±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.
- CAS No.
- 142273-20-9
- Jingsj CID
- J-1976334-9
- Molecular Formula
- C16H11BrN2O
- Molecular Weight
- 327.175 g/mol
- Category
- Ketones
- Last updated
- 11/3/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | >300ºC (dec.) |
|---|---|
| Boiling Point | 613.0±45.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 324.5±28.7 °C |
| Exact Mass | 326.005463 |
| PSA | 44.89000 |
| LogP | 4.02 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.730 |
| Storage Conditions | 2-8°C |
| Additional Property | DMSO: 18 mg/mL, clear, yellow |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Cdk1/cyclin B:0.4 μM (IC50) cdk2/cyclin A:0.68 μM (IC50) CDK5/p35:0.85 μM (IC50) CDK2/cyclinE:7.5 μM (IC50) GSK-3β:0.023 μM (IC50) erk1:20 μM (IC50) erk2:9 μM (IC50) c-raf:38 μM (IC50) |
|---|---|
| Additional Information | [1]. Zaharevitz DW, et al. Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases. Cancer Res. 1999 Jun 1;59(11):2566-9. [2]. Lyssiotis CA, et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):8912-7. |
Frequently Asked Questions
What is the CAS number of Kenpaullone?
The CAS number of Kenpaullone is 142273-20-9.
What are the molecular formula and molecular weight of Kenpaullone?
Kenpaullone has molecular formula C16H11BrN2O and molecular weight 327.175 g/mol.
Is Kenpaullone hazardous?
Kenpaullone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Kenpaullone?
For Kenpaullone, Upstream Products: 3,4-dihydro-1H-1-benzazepine-2,5-dione, (4-Bromophenyl)hydrazine, 4-Bromophenylhydrazine hydrochloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Kenpaullone (CAS 142273-20-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1976334-9 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.