5-Iodotubercidin

Also known as: 5-Iodotubercidin, ITU, NSC 113939, 7-Iodo-7-deazaadenosine, 4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine, 5-Iodo-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Iodotubercidin, 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-β-D-ribofuranosyl-, MFCD00055131

5-Iodotubercidin (CAS 24386-93-4) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C11H13IN4O4 and a molecular weight of 392.150 g/mol. Key properties include a melting point of 216-217ºC dec., a boiling point of 701.5±60.0 °C at 760 mmHg, a density of 2.5±0.1 g/cm3 and a flash point of 378.0±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 24386-93-4
Jingsj CID: J-1976318-9
Molecular Formula: C₁₁H₁₃IN₄O₄
Molecular Weight: 392.150 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	216-217ºC dec.
Boiling Point	701.5±60.0 °C at 760 mmHg
Density	2.5±0.1 g/cm3
Flash Point	378.0±32.9 °C
Exact Mass	391.998138
PSA	126.65000
LogP	0.91
Vapor Pressure	0.0±2.3 mmHg at 25°C
Refractive Index	1.919
Storage Conditions	2-8℃
Stability	Store tightly sealed at 4°C; Light Sensitive
Additional Property	0.1 M HCl: 0.7 mg/mL

Activity & Biological Data

Target	IC50: 26 nM (adenosine kinase)
Additional Information	[1]. Massillon D, et al. Identification of the glycogenic compound 5-iodotubercidin as a general protein kinase inhibitor. Biochem J. 1994 Apr 1;299 (Pt 1):123-8. [2]. Ugarkar BG, et al. Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues. J Med Chem. 2000 Jul 27;43(15):2883-93. [3]. García-Villafranca J, et al. Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. Biochem Pharmacol. 2002 Jun 1;63(11):1997-2000. [4]. De Antoni A, et al. A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. J Cell Biol. 2012 Oct 15;199(2):269-84. [5]. Acharya MM, et al. Adenosine Kinase Inhibition Protects against Cranial Radiation-Induced Cognitive Dysfunction. Front Mol Neurosci. 2016 Jun 3;9:42.

Target

IC50: 26 nM (adenosine kinase)

Additional Information

[1]. Massillon D, et al. Identification of the glycogenic compound 5-iodotubercidin as a general protein kinase inhibitor. Biochem J. 1994 Apr 1;299 (Pt 1):123-8. [2]. Ugarkar BG, et al. Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues. J Med Chem. 2000 Jul 27;43(15):2883-93. [3]. García-Villafranca J, et al. Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. Biochem Pharmacol. 2002 Jun 1;63(11):1997-2000. [4]. De Antoni A, et al. A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. J Cell Biol. 2012 Oct 15;199(2):269-84. [5]. Acharya MM, et al. Adenosine Kinase Inhibition Protects against Cranial Radiation-Induced Cognitive Dysfunction. Front Mol Neurosci. 2016 Jun 3;9:42.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5-Iodotubercidin?

The CAS number of 5-Iodotubercidin is 24386-93-4.

What are the molecular formula and molecular weight of 5-Iodotubercidin?

5-Iodotubercidin has molecular formula C11H13IN4O4 and molecular weight 392.150 g/mol.

What are the upstream and downstream products of 5-Iodotubercidin?

For 5-Iodotubercidin, Upstream Products: 4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine, 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5-Iodotubercidin (CAS 24386-93-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1976318-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.