Tanshinone IIA

Also known as: Tanshinone IIA, Tanshinone II, Tanshinone B, Dan Shen Ketone, NSC 686518, NSC 686519, Tashinone IIA, 1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione

Tanshinone IIA (CAS 568-72-9) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C19H18O3 and a molecular weight of 294.344 g/mol. Key properties include a melting point of 205-207ºC, a boiling point of 480.7±44.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 236.4±21.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 568-72-9
Jingsj CID: J-1975612-1
Molecular Formula: C₁₉H₁₈O₃
Molecular Weight: 294.344 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	205-207ºC
Boiling Point	480.7±44.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	236.4±21.1 °C
Exact Mass	294.125580
PSA	47.28000
LogP	5.47
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.588
Storage Conditions	2-8°C

Activity & Biological Data

Target	VEGF/VEGFR2[1]
Additional Information	[1]. Xie J, et al. The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line. Acta Pharm Sin B. 2015 Nov;5(6):554-63. [2]. Zhang Z, et al. Tanshinone IIA inhibits apoptosis in the myocardium by inducing microRNA-152-3p expression and thereby downregulating PTEN. Am J Transl Res. 2016 Jul 15;8(7):3124-32. [3]. Su CC, et al. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo. Oncol Rep. 2016 Aug;36(2):1173-9.

Target

VEGF/VEGFR2[1]

Additional Information

[1]. Xie J, et al. The antitumor effect of tanshinone IIA on anti-proliferation and decreasing VEGF/VEGFR2 expression on the human non-small cell lung cancer A549 cell line. Acta Pharm Sin B. 2015 Nov;5(6):554-63. [2]. Zhang Z, et al. Tanshinone IIA inhibits apoptosis in the myocardium by inducing microRNA-152-3p expression and thereby downregulating PTEN. Am J Transl Res. 2016 Jul 15;8(7):3124-32. [3]. Su CC, et al. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo. Oncol Rep. 2016 Aug;36(2):1173-9.

Frequently Asked Questions

What is the CAS number of Tanshinone IIA?

The CAS number of Tanshinone IIA is 568-72-9.

What are the molecular formula and molecular weight of Tanshinone IIA?

Tanshinone IIA has molecular formula C19H18O3 and molecular weight 294.344 g/mol.

What are the upstream and downstream products of Tanshinone IIA?

For Tanshinone IIA, Upstream Products: Cryptotanshinone, 5-Bromo-2-methyl-2-pentene, 2-Bromoanisole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tanshinone IIA (CAS 568-72-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975612-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.