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Cryptotanshinone

Also known as: (R)-1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-phenanthro[1,2-b]furan-10,11-dione, Tanshinone C, (R)-(−)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione, Cryptotanshinone (constituent of Salvia miltiorrhiza)

Cryptotanshinone (CAS 35825-57-1) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C19H20O3 and a molecular weight of 296.360 g/mol. Key properties include a melting point of 184-185ºC, a boiling point of 459.0±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 203.4±28.8 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H410 — Very toxic to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
35825-57-1
Jingsj CID
J-1975556-8
Molecular Formula
C19H20O3
Molecular Weight
296.360 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point184-185ºC
Boiling Point459.0±45.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point203.4±28.8 °C
Exact Mass296.141235
PSA43.37000
LogP4.93
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.603
Storage ConditionsStore at RT

GHS Safety & Compliance

Acute Toxicity / Environmental HazardSignal word: Danger
  • H301 — Toxic if swallowed
  • H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

TargetSTAT3:4.6 μM (IC50)
Additional Information[1]. Shin DS, et al. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells. Cancer Res. 2009 Jan 1;69(1):193-202. [2]. Huang Y, et al. Cryptotanshinone reverses ovarian insulin resistance in mice through activation of insulin signaling and the regulation of glucose transporters and hormone synthesizing enzymes. Fertil Steril. 2014 Aug;102(2):589-596.e4. [3]. Ge Y, et al. Cryptotanshinone acts synergistically with imatinib to induce apoptosis of human chronic myeloid leukemia cells. Leuk Lymphoma. 2014 Jun 25:1-9. [4]. Kim EJ, et al. Antidiabetes and antiobesity effect of cryptotanshinone via activation of AMP-activated protein kinase. Mol Pharmacol. 2007 Jul;72(1):62-72. Epub 2007 Apr 11.

Customs & Trade Information

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Cryptotanshinone?

The CAS number of Cryptotanshinone is 35825-57-1.

What are the molecular formula and molecular weight of Cryptotanshinone?

Cryptotanshinone has molecular formula C19H20O3 and molecular weight 296.360 g/mol.

Is Cryptotanshinone hazardous?

Cryptotanshinone has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H410 — Very toxic to aquatic life with long lasting effects.

What are the upstream and downstream products of Cryptotanshinone?

For Cryptotanshinone, Upstream Products: 5-Bromo-2-methyl-2-pentene, 2-Bromoanisole, Anisole; Downstream Products: Tanshinone IIA.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Cryptotanshinone (CAS 35825-57-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975556-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.