Oroxylin A

Also known as: Baicalein 6-methyl ether, 6-Methoxybaicalein, 5,7-Dihydroxy-6-methoxyflavone, 5,7-Dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one, Oroxylin, OLOXYLINA, oxoxylin A

Oroxylin A (CAS 480-11-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H12O5 and a molecular weight of 284.263 g/mol. Key properties include a melting point of 195-197ºC, a boiling point of 540.9±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 207.4±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 480-11-5
Jingsj CID: J-1975233-1
Molecular Formula: C₁₆H₁₂O₅
Molecular Weight: 284.263 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	195-197ºC
Boiling Point	540.9±50.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	207.4±23.6 °C
Exact Mass	284.068481
PSA	79.90000
LogP	2.37
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.669
Storage Conditions	2-8°C

Activity & Biological Data

Additional Information	[1]. Zhao K, et al. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. J Hematol Oncol. 2015 Apr 23;8:41. http://www.ncbi.nlm.nih.gov/pubmed/25902914 [2]. Dai Q, et al. Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia-inducible factor-1 in human hepatoma HepG2 cells. Mol Carcinog. 2015 Aug 10. [3]. Wei L, et al. Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization. Cell Death Dis. 2015 Apr 9

Additional Information

[1]. Zhao K, et al. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. J Hematol Oncol. 2015 Apr 23;8:41. http://www.ncbi.nlm.nih.gov/pubmed/25902914 [2]. Dai Q, et al. Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia-inducible factor-1 in human hepatoma HepG2 cells. Mol Carcinog. 2015 Aug 10. [3]. Wei L, et al. Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization. Cell Death Dis. 2015 Apr 9

Frequently Asked Questions

What is the CAS number of Oroxylin A?

The CAS number of Oroxylin A is 480-11-5.

What are the molecular formula and molecular weight of Oroxylin A?

Oroxylin A has molecular formula C16H12O5 and molecular weight 284.263 g/mol.

What are the upstream and downstream products of Oroxylin A?

For Oroxylin A, Upstream Products: 5,6,7-Trimethoxyflavone, Baicalein, iodomethane; Downstream Products: Baicalein, 5,6,7-Trimethoxyflavone, Mosloflavone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Oroxylin A (CAS 480-11-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975233-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.