Baicalein
Also known as: 5,6,7-Trihydroxyflavone, 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Noroxylin, MFCD00017459, Baicelein
Baicalein (CAS 491-67-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H10O5 and a molecular weight of 270.237 g/mol. Key properties include a melting point of 256-271 °C(lit.), a boiling point of 575.9±50.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 225.3±23.6 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 491-67-8
- Jingsj CID
- J-18822-7
- Molecular Formula
- C15H10O5
- Molecular Weight
- 270.237 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 256-271 °C(lit.) |
|---|---|
| Boiling Point | 575.9±50.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 225.3±23.6 °C |
| Exact Mass | 270.052826 |
| PSA | 90.90000 |
| LogP | 3.31 |
| Vapor Pressure | 0.0±1.7 mmHg at 25°C |
| Refractive Index | 1.732 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | IC50: 3.12 mM (xanthine oxidase)[1] |
|---|---|
| Additional Information | [1]. Shieh DE,et al. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res. 2000 Sep-Oct;20(5A):2861-5. [2]. Patwardhan RS, et al. Baicalein exhibits anti-inflammatory effects via inhibition of NF-κB transactivation. Biochem Pharmacol. 2016 May 15;108:75-89. [3]. Ma X, et al. Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway.Drug Des Devel Ther. 2016 Apr 18;10:1419-41. [4]. Kong EK, et al. A novel anti-fibrotic agent, baicalein, for the treatment of myocardial fibrosis in spontaneously hypertensiverats. Eur J Pharmacol. 2011 May 11;658(2-3):175-81. |
Customs & Trade Information
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Baicalein?
The CAS number of Baicalein is 491-67-8.
What are the molecular formula and molecular weight of Baicalein?
Baicalein has molecular formula C15H10O5 and molecular weight 270.237 g/mol.
Is Baicalein hazardous?
Baicalein has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Baicalein?
For Baicalein, Upstream Products: 5,6,7-Trimethoxyflavone, Negletein, Baicalin; Downstream Products: Oroxylin A, Mosloflavone, Negletein.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Baicalein (CAS 491-67-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18822-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.