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N-BOC-trans-4-hydroxy-D-proline methyl ester

Also known as: Boc-trans-D-Hyp-OMe, (2R,4S)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, N-Boc-trans-4-hydroxy-D-proline methyl ester, Boc-trans-4-hydroxy-D-proline methyl ester, (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4S)-, 1-O-tert-butyl 2-O-methyl (2R,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

N-BOC-trans-4-hydroxy-D-proline methyl ester (CAS 135042-17-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C11H19NO5 and a molecular weight of 245.272 g/mol. Key properties include a boiling point of 387.6±42.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 188.2±27.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
135042-17-0
Jingsj CID
J-1975185-0
Molecular Formula
C11H19NO5
Molecular Weight
245.272 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point387.6±42.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point188.2±27.9 °C
Exact Mass245.126328
PSA76.07000
LogP-0.17
Vapor Pressure0.0±2.0 mmHg at 25°C
Refractive Index1.520
Storage Conditions2-8°C

Activity & Biological Data

TargetNon-cleavable
Additional Information[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Frequently Asked Questions

What is the CAS number of N-BOC-trans-4-hydroxy-D-proline methyl ester?

The CAS number of N-BOC-trans-4-hydroxy-D-proline methyl ester is 135042-17-0.

What are the molecular formula and molecular weight of N-BOC-trans-4-hydroxy-D-proline methyl ester?

N-BOC-trans-4-hydroxy-D-proline methyl ester has molecular formula C11H19NO5 and molecular weight 245.272 g/mol.

What are the upstream and downstream products of N-BOC-trans-4-hydroxy-D-proline methyl ester?

For N-BOC-trans-4-hydroxy-D-proline methyl ester, Downstream Products: (2S,4R)-1-tert-Butyl 2-methyl 4-((methylsulfonyl)oxy)pyrrolidine-1,2-dicarboxylate, trans-4-Hydroxy-D-proline hydrochloride, N-Boc-4-oxo-D-proline methyl ester.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-BOC-trans-4-hydroxy-D-proline methyl ester (CAS 135042-17-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975185-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.