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2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione

Also known as: (R)-2-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione, 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone, 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]-, Rivaroxaban intermediate B, Rivaroxaban impurity 39, Rivaroxaban phthalimide dicarbonyl impurity

2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione (CAS 446292-07-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C21H21N3O5 and a molecular weight of 395.409 g/mol. Key properties include a boiling point of 734.9±60.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 398.3±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
446292-07-5
Jingsj CID
J-1972003-7
Molecular Formula
C21H21N3O5
Molecular Weight
395.409 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point734.9±60.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point398.3±32.9 °C
Exact Mass395.148132
PSA99.18000
LogP1.02
Vapor Pressure0.0±2.5 mmHg at 25°C
Refractive Index1.672

Frequently Asked Questions

What is the CAS number of 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione?

The CAS number of 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione is 446292-07-5.

What are the molecular formula and molecular weight of 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione?

2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione has molecular formula C21H21N3O5 and molecular weight 395.409 g/mol.

What are the upstream and downstream products of 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione?

For 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione, Upstream Products: (S)-(+)-Glycidyl Phthalimide, 4-(4-Aminophenyl)morpholin-3-one, (R)-4-[4-[(3-Chloro-2-hydroxypropyl)amino]phenyl]morpholin-3-one; Downstream Products: Rivaroxaban, 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone hydrochloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione (CAS 446292-07-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1972003-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.