Rivaroxaban

Also known as: (S)-Rivaroxaban, 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide, 5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide, BAY 59-7939, Xarelto

Rivaroxaban (CAS 366789-02-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H18ClN3O5S and a molecular weight of 435.881 g/mol. Key properties include a melting point of 228-229°C, a boiling point of 732.6±60.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 396.9±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 366789-02-8
Jingsj CID: J-1963082-1
Molecular Formula: C₁₉H₁₈ClN₃O₅S
Molecular Weight: 435.881 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	228-229°C
Boiling Point	732.6±60.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	396.9±32.9 °C
Exact Mass	435.065582
PSA	116.42000
LogP	1.84
Vapor Pressure	0.0±2.4 mmHg at 25°C
Refractive Index	1.633
Storage Conditions	Refrigerator

Activity & Biological Data

Target	IC50: 0.7 nM (FXa)[1] Ki: 0.4 nM (FXa)[1]
Additional Information	[1]. Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19) [2]. Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3(3):514-21.

Target

IC50: 0.7 nM (FXa)[1] Ki: 0.4 nM (FXa)[1]

Additional Information

[1]. Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19) [2]. Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3(3):514-21.

Frequently Asked Questions

What is the CAS number of Rivaroxaban?

The CAS number of Rivaroxaban is 366789-02-8.

What are the molecular formula and molecular weight of Rivaroxaban?

Rivaroxaban has molecular formula C19H18ClN3O5S and molecular weight 435.881 g/mol.

What are the upstream and downstream products of Rivaroxaban?

For Rivaroxaban, Upstream Products: 5-Chlorothiophene-2-carbonyl chloride, 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone hydrochloride, 5-Chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-2-thiophenecarboxamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Rivaroxaban (CAS 366789-02-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963082-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.