LY518674

Also known as: 2-Methyl-2-[4-[3-[1-(4-Methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid, 2-[4-[3-[2,5-dihydro-1-[(4-methylphenyl)methyl]-5-oxo-1H-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methyl-propanoic acid, 2-[4-[3-[2,5-dihydro-1-[(4-methylphenyl)methyl]-5-oxo-1H-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methylpropanoic acid, 2-[4-[3-[4,5-dihydro-1-[(4-methylphenyl)methyl]-5-oxo-1H-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methylpropanoic acid, Propanoic acid,2-[4-[3-[2,5-dihydro-1-[(4-methylphenyl)methyl]-5-oxo-1H-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methyl

LY518674 (CAS 425671-29-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C23H27N3O4 and a molecular weight of 409.47800 g/mol. Key properties include a boiling point of 575.852ºC at 760 mmHg, a density of 1.21g/cm3 and a flash point of 302.065ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 425671-29-0
Jingsj CID: J-1970638-8
Molecular Formula: C₂₃H₂₇N₃O₄
Molecular Weight: 409.47800 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	575.852ºC at 760 mmHg
Density	1.21g/cm3
Flash Point	302.065ºC
Exact Mass	409.20000
PSA	97.21000
LogP	3.34540
Refractive Index	1.594
Storage Conditions	2-8°C

Activity & Biological Data

Target	EC50: 42 nM (human PPARα)[1]
Additional Information	[1]. Bravo Y, et al. Identification of the first potent, selective and bioavailable PPARα antagonist. Bioorg Med Chem Lett. 2014 May 15;24(10):2267-72. [2]. Nissen SE, et al. Effects of a potent and selective PPAR-alpha agonist in patients with atherogenic dyslipidemia or hypercholesterolemia: two randomized controlled trials. JAMA. 2007 Mar 28;297(12):1362-73. [3]. Khera AV, et al. Potent peroxisome proliferator-activated receptor-α agonist treatment increases cholesterol efflux capacity in humans with the metabolic syndrome. Eur Heart J. 2015 Nov 14;36(43):3020-2.

Target

EC50: 42 nM (human PPARα)[1]

Additional Information

[1]. Bravo Y, et al. Identification of the first potent, selective and bioavailable PPARα antagonist. Bioorg Med Chem Lett. 2014 May 15;24(10):2267-72. [2]. Nissen SE, et al. Effects of a potent and selective PPAR-alpha agonist in patients with atherogenic dyslipidemia or hypercholesterolemia: two randomized controlled trials. JAMA. 2007 Mar 28;297(12):1362-73. [3]. Khera AV, et al. Potent peroxisome proliferator-activated receptor-α agonist treatment increases cholesterol efflux capacity in humans with the metabolic syndrome. Eur Heart J. 2015 Nov 14;36(43):3020-2.

Frequently Asked Questions

What is the CAS number of LY518674?

The CAS number of LY518674 is 425671-29-0.

What are the molecular formula and molecular weight of LY518674?

LY518674 has molecular formula C23H27N3O4 and molecular weight 409.47800 g/mol.

What are the upstream and downstream products of LY518674?

For LY518674, Upstream Products: tert-butyl 2-[4-(4-hydrazinyl-4-oxobutyl)phenoxy]-2-methylpropanoate, Methyl 4-(4-methoxyphenyl)butanoate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "LY518674 (CAS 425671-29-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970638-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.