2'-O-Methylguanosine

Also known as: 2'-O-Methyl Guanosine, 2'-OMe Guanosine, 2'-OMe-G, Gm19, Guanosine, 2'-O-methyl-, O2'-methyl-guanosine, UNII-W722H4PA1S, MFCD00057053

2'-O-Methylguanosine (CAS 2140-71-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C11H15N5O5 and a molecular weight of 297.267 g/mol. Key properties include a melting point of 218-220ºC, a boiling point of 711.7ºC at 760 mmHg, a density of 2.0±0.1 g/cm3 and a flash point of 384.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 2140-71-8
Jingsj CID: J-1970406-4
Molecular Formula: C₁₁H₁₅N₅O₅
Molecular Weight: 297.267 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	218-220ºC
Boiling Point	711.7ºC at 760 mmHg
Density	2.0±0.1 g/cm3
Flash Point	384.2ºC
Exact Mass	297.107330
PSA	148.51000
LogP	-0.36
Vapor Pressure	2.93E-21mmHg at 25°C
Refractive Index	1.829
Storage Conditions	Refrigerator

Activity & Biological Data

Additional Information	[1]. B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7. [2]. T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2'-O-Methylguanosine?

The CAS number of 2'-O-Methylguanosine is 2140-71-8.

What are the molecular formula and molecular weight of 2'-O-Methylguanosine?

2'-O-Methylguanosine has molecular formula C11H15N5O5 and molecular weight 297.267 g/mol.

What are the upstream and downstream products of 2'-O-Methylguanosine?

For 2'-O-Methylguanosine, Upstream Products: 2-Amino-2'-O-methyladenosine, Trimethylsulfonium hydroxide, Guanosine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2'-O-Methylguanosine (CAS 2140-71-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970406-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.