4μ8C

Also known as: 8-formyl-7-hydroxy-4-methylcoumarin, 7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde, 7-hydroxy-4-methyl-2-oxo-2H-chromen-8-carbaldehyde, 4-Methyl-7-hydroxy-8-formylcoumarin, IRE1 Inhibitor III, 4u8C, 4U8C

4μ8C (CAS 14003-96-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C11H8O4 and a molecular weight of 204.17900 g/mol. Key properties include a melting point of 189-190 ºC (ethanol ) and a density of 1.406±0.06 g/cm3 (20 ºC 760 Torr). It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 14003-96-4
Jingsj CID: J-1970068-6
Molecular Formula: C₁₁H₈O₄
Molecular Weight: 204.17900 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	189-190 ºC (ethanol )
Density	1.406±0.06 g/cm3 (20 ºC 760 Torr)
Exact Mass	204.04200
PSA	67.51000
LogP	1.61950
Storage Conditions	-20℃
Additional Property	Very slightly soluble (0.59 g/L) (25 ºC)

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Additional Information	[1]. Cross BC, et al. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E869-78. [2]. Zhang L, et al. IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. BMC Cell Biol. 2014 Jul 10;15:29. [3]. Kemp K, et al. The serine-threonine kinase inositol-requiring enzyme 1α (IRE1α) promotes IL-4 production in T helper cells. J Biol Chem. 2013 Nov 15;288(46):33272-82.

Additional Information

[1]. Cross BC, et al. The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E869-78. [2]. Zhang L, et al. IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. BMC Cell Biol. 2014 Jul 10;15:29. [3]. Kemp K, et al. The serine-threonine kinase inositol-requiring enzyme 1α (IRE1α) promotes IL-4 production in T helper cells. J Biol Chem. 2013 Nov 15;288(46):33272-82.

Customs & Trade Information

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4μ8C?

The CAS number of 4μ8C is 14003-96-4.

What are the molecular formula and molecular weight of 4μ8C?

4μ8C has molecular formula C11H8O4 and molecular weight 204.17900 g/mol.

Is 4μ8C hazardous?

4μ8C has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of 4μ8C?

For 4μ8C, Upstream Products: 4-Methylumbelliferone, 7-Allyloxy-4-methylcoumarin, acetic acid; Downstream Products: 7-Hydroxy-4,8-dimethyl-2H-chromen-2-one, 4-Methyldaphnetin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4μ8C (CAS 14003-96-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970068-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.