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2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine

Also known as: UNC0638, UNC-0638, CS-565, UNII-26A103L2FO, 2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine, 2-Cyclohexyl-N-(1-isopropyl-4-piperidinyl)-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine, 4-Quinazolinamine, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-, cc-643

2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine (CAS 1255580-76-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C30H47N5O2 and a molecular weight of 509.727 g/mol. Key properties include a melting point of 93-94 ºC, a boiling point of 563.9±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 294.8±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1255580-76-7
Jingsj CID
J-1968265-6
Molecular Formula
C30H47N5O2
Molecular Weight
509.727 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point93-94 ºC
Boiling Point563.9±50.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point294.8±30.1 °C
Exact Mass509.372986
PSA62.75000
LogP5.75
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.587
Storage Conditions-20℃
Additional PropertyPractically insoluble (0.012 g/L) (25 ºC)

Activity & Biological Data

TargetIC50: <15 nM (G9a), 19±1 nM (GLP)[1]
Additional Information[1]. Vedadi M, et al. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol. 2011 Jul 10;7(8):566-74. [2]. Fu L, et al. Effects of the Histone Methyltransferase Inhibitor UNC0638 on Histone H3K9 Dimethylation of Cultured Ovine Somatic Cells and Development of Resulting Early Cloned Embryos. Reprod Domest Anim. 2014 Apr;49(2):e21-5.

Frequently Asked Questions

What is the CAS number of 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine?

The CAS number of 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine is 1255580-76-7.

What are the molecular formula and molecular weight of 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine?

2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine has molecular formula C30H47N5O2 and molecular weight 509.727 g/mol.

What are the upstream and downstream products of 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine?

For 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine, Upstream Products: 3-(1-Pyrrolidinyl)-1-propanol, 4-Hydroxy-3-methoxybenzonitrile, 4-(Benzyloxy)-3-methoxybenzonitrile.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine (CAS 1255580-76-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1968265-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.