Sunitinib Malate
Also known as: SU 11248, SU011248, SU112248, Sunitinib L-malic acid salt, Sunitinib (Malate), N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt, Sunitinib L-malate, EZSolution Sunitinib Malate
Sunitinib Malate (CAS 341031-54-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C26H33FN4O7 and a molecular weight of 532.561 g/mol. Key properties include a melting point of 189-191°C, a boiling point of 156 °C(lit.), a density of 1.3600 g/mL at 25 °C(lit.) and a flash point of 72.8 °C. It is classified under GHS with signal word Danger and hazard statements H360 — May damage fertility or the unborn child and H372 — Causes damage to organs through prolonged exposure. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.
- CAS No.
- 341031-54-7
- Jingsj CID
- J-1963045-6
- Molecular Formula
- C26H33FN4O7
- Molecular Weight
- 532.561 g/mol
- Category
- Organic Acids
- Last updated
- 11/2/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 189-191°C |
|---|---|
| Boiling Point | 156 °C(lit.) |
| Density | 1.3600 g/mL at 25 °C(lit.) |
| Flash Point | 72.8 °C |
| Exact Mass | 532.233337 |
| PSA | 172.06000 |
| LogP | 2.77040 |
| Refractive Index | n20/D 1.455(lit.) |
| Storage Conditions | Store at +4°C |
GHS Safety & Compliance
- H360 — May damage fertility or the unborn child
- H372 — Causes damage to organs through prolonged exposure
Activity & Biological Data
| Target | VEGFR2:80 nM (IC50) PDGFRβ:2 nM (IC50) |
|---|---|
| Additional Information | [1]. Sun L, et al. Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor r [2]. Mendel DB, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Can [3]. O'Farrell AM, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood. 2003 May 1;101(9):3597-605. [4]. Mousseau Y, et al. Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model. Breast Cancer Res Treat. 2012 Jul;134(1):31-40. [5]. Small J, et al. The addition of abemaciclib to sunitinib induces regression of renal cell carcinoma xenograft tumors. Oncotarget. 2017 Jul 27;8(56):95116-95134. |
Frequently Asked Questions
What is the CAS number of Sunitinib Malate?
The CAS number of Sunitinib Malate is 341031-54-7.
What are the molecular formula and molecular weight of Sunitinib Malate?
Sunitinib Malate has molecular formula C26H33FN4O7 and molecular weight 532.561 g/mol.
Is Sunitinib Malate hazardous?
Sunitinib Malate has GHS signal word Danger and hazard statements H360 — May damage fertility or the unborn child; H372 — Causes damage to organs through prolonged exposure.
What are the upstream and downstream products of Sunitinib Malate?
For Sunitinib Malate, Upstream Products: L-(-)-Malic acid, N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide, 5-Fluoro-2-oxindole.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Sunitinib Malate (CAS 341031-54-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963045-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.