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Rimonabant hydrochloride

Also known as: SR 141716A, Acomplia, 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide hydrochloride, 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride, 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-, hydrochloride (1:1), 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide hydrochloride, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-n-1-piperidinyl-1h-pyrazole-3-carboxamide monohydrochloride, Rimonabant HCl, Rimonabant (Hydrochloride), MFCD04034714

Rimonabant hydrochloride (CAS 158681-13-1) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C22H22Cl4N4O and a molecular weight of 500.248 g/mol. Key properties include a melting point of 230-240ºC, a boiling point of 627.6ºC at 760 mmHg and a flash point of 333.3ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
158681-13-1
Jingsj CID
J-1961668-3
Molecular Formula
C22H22Cl4N4O
Molecular Weight
500.248 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point230-240ºC
Boiling Point627.6ºC at 760 mmHg
Flash Point333.3ºC
Exact Mass498.054779
PSA50.16000
LogP7.06940
Storage Conditions-20°C Freezer

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H301 — Toxic if swallowed
  • H319 — Causes serious eye irritation

Activity & Biological Data

TargetKi: 2 nM (CB1 receptor)[1]
Additional Information[1]. Vivian JA, et al. Analgesic, respiratory and heart rate effects of cannabinoid and opioid agonists in rhesus monkeys: antagonist effects of SR 141716A. J Pharmacol Exp Ther. 1998 Aug;286(2):697-703. [2]. Netherland C, et al. Rimonabant is a dual inhibitor of acyl CoA:cholesterol acyltransferases 1 and 2. Biochem Biophys Res Commun. 2010 Aug 6;398(4):671-6. [3]. Rodríguez-Arias M, et al. Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait. Neural Plast. 2016;2016:6481862.

Frequently Asked Questions

What is the CAS number of Rimonabant hydrochloride?

The CAS number of Rimonabant hydrochloride is 158681-13-1.

What are the molecular formula and molecular weight of Rimonabant hydrochloride?

Rimonabant hydrochloride has molecular formula C22H22Cl4N4O and molecular weight 500.248 g/mol.

Is Rimonabant hydrochloride hazardous?

Rimonabant hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Rimonabant hydrochloride?

For Rimonabant hydrochloride, Upstream Products: 1-Aminopiperidine, Rimonabant, 4'-Chloropropiophenone; Downstream Products: Rimonabant.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Rimonabant hydrochloride (CAS 158681-13-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961668-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.