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Nalmefene

Also known as: (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol, (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol, 17-(Cyclopropylmethyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diol, 6-Deoxo-6-methylenenaltrexone, 6-Desoxy-6-methylenenaltrexone, Alcofene, Arthene, Cervene, Nalmefenum, Nalmetrene, Nalmetreno, Nalmetrenum, Revex, [5α]-17-[Cyclopropylmethyl]-4,5-epoxy-6-methylenemorphinan-3,14-diol, (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol

Nalmefene (CAS 55096-26-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H25NO3 and a molecular weight of 339.43 g/mol. Key property: a melting point of 188 - 190ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
55096-26-9
Jingsj CID
J-1959925-8
Molecular Formula
C21H25NO3
Molecular Weight
339.43 g/mol
Category
Organic Compounds
Last updated
8/21/2026
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Physicochemical Properties

Melting Point188 - 190ºC
Exact Mass339.18300
PSA52.93000
LogP2.45040
Storage Conditions2-8°C

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetMOR, DOR, KOR[1]
Additional Information[1]. Wang DS, et al. Nalmefene: a long-acting opioid antagonist. Clinical applications in emergency medicine. J Emerg Med. 1998 May-Jun;16(3):471-5. [2]. Mann K, et al. Nalmefene for the management of alcohol dependence: review on its pharmacology, mechanism of action and meta-analysis on its clinical efficacy. Eur Neuropsychopharmacol. 2016 Dec;26(12):1941-1949.

Frequently Asked Questions

What is the CAS number of Nalmefene?

The CAS number of Nalmefene is 55096-26-9.

What are the molecular formula and molecular weight of Nalmefene?

Nalmefene has molecular formula C21H25NO3 and molecular weight 339.43 g/mol.

Is Nalmefene hazardous?

Nalmefene has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Nalmefene?

For Nalmefene, Upstream Products: naltrexone, Methyltriphenylphosphonium bromide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Nalmefene (CAS 55096-26-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959925-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.