Dehydroandrographolide

Also known as: 14-Deoxy-11,12-didehydroandrographolide, 14-Deoxy-11-dehydroandrographolide, Andrographolide, dehydro-, Dehydroanddrographolide, Dehydroandrographoline, Dehydrographkide, (3E)-3-[2-[(1S,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone

Dehydroandrographolide (CAS 134418-28-3) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C20H28O4 and a molecular weight of 332.43 g/mol. Key properties include a boiling point of 512.8±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 178.3±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 134418-28-3
Jingsj CID: J-1959634-7
Molecular Formula: C₂₀H₂₈O₄
Molecular Weight: 332.43 g/mol
Category: Esters
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Boiling Point	512.8±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	178.3±23.6 °C
PSA	86.99000
LogP	2.97
Vapor Pressure	0.0±3.0 mmHg at 25°C
Refractive Index	1.584

Activity & Biological Data

Additional Information	[1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6. [2]. Chao WW, et al. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5:17. [3]. Basak A, et al. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J. 1999 Feb 15;338 ( Pt 1):107-13. [4]. Zhu T, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41. [5]. Chen H, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9.

Additional Information

[1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6. [2]. Chao WW, et al. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5:17. [3]. Basak A, et al. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J. 1999 Feb 15;338 ( Pt 1):107-13. [4]. Zhu T, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41. [5]. Chen H, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9.

Frequently Asked Questions

What is the CAS number of Dehydroandrographolide?

The CAS number of Dehydroandrographolide is 134418-28-3.

What are the molecular formula and molecular weight of Dehydroandrographolide?

Dehydroandrographolide has molecular formula C20H28O4 and molecular weight 332.43 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Dehydroandrographolide (CAS 134418-28-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959634-7 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.