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14-Deoxy-11,12-didehydroandrographolide

Also known as: Dehydroandrographolide, 11,12-Didehydro-14-deoxyandrographolide, AP 10, ent-(3β,11E)-3,19-Dihydroxy-8(17),11,13-labdatrien-16,15-olide, 3-[(E)-2-[(1R,4aS,5R,6R,8aR)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethenyl]-2(5H)-furanone

14-Deoxy-11,12-didehydroandrographolide (CAS 42895-58-9) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C20H28O4 and a molecular weight of 332.434 g/mol. Key properties include a melting point of 204-205ºC, a boiling point of 519.6±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 182.4±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
42895-58-9
Jingsj CID
J-1955090-9
Molecular Formula
C20H28O4
Molecular Weight
332.434 g/mol
Category
Esters
Last updated
8/21/2026

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Physicochemical Properties

Melting Point204-205ºC
Boiling Point519.6±50.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point182.4±23.6 °C
Exact Mass332.198761
PSA66.76000
LogP1.89
Vapor Pressure0.0±3.1 mmHg at 25°C
Refractive Index1.567
Storage Conditions-20°C

Activity & Biological Data

TargetNF-κB
Additional Information[1]. Guan SP, et al. Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue ofandrographolide, in allergic airway inflammation. J Nat Prod. 2011 Jun 24;74(6):1484-90.

Frequently Asked Questions

What is the CAS number of 14-Deoxy-11,12-didehydroandrographolide?

The CAS number of 14-Deoxy-11,12-didehydroandrographolide is 42895-58-9.

What are the molecular formula and molecular weight of 14-Deoxy-11,12-didehydroandrographolide?

14-Deoxy-11,12-didehydroandrographolide has molecular formula C20H28O4 and molecular weight 332.434 g/mol.

What are the upstream and downstream products of 14-Deoxy-11,12-didehydroandrographolide?

For 14-Deoxy-11,12-didehydroandrographolide, Upstream Products: Methanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "14-Deoxy-11,12-didehydroandrographolide (CAS 42895-58-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955090-9 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.