4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

Also known as: (rac)-Exatecan Intermediate 1, 4-Ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10-trione, 7,8-Dihydro-4-ethyl-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione

4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione (CAS 102978-40-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C13H13NO5 and a molecular weight of 263.25 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 102978-40-5
Jingsj CID: J-1959403-7
Molecular Formula: C₁₃H₁₃NO₅
Molecular Weight: 263.25 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	263.07900
PSA	85.60000
LogP	0.08910

Activity & Biological Data

Additional Information	[1]. Weng W, et al. Antibody-Exatecan Conjugates with a Novel Self-immolative Moiety Overcome Resistance in Colon and Lung Cancer. Cancer Discov. 2023 Apr 3;13(4):950-973. [2]. Zhang Hongwei, et al. Intermediate for synthesizing camptothecin derivatives using exatecan mesylate and its preparation method and application. China, CN111470998. 2020-07-31.

Frequently Asked Questions

What is the CAS number of 4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione?

The CAS number of 4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is 102978-40-5.

What are the molecular formula and molecular weight of 4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione?

4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione has molecular formula C13H13NO5 and molecular weight 263.25 g/mol.

What are the upstream and downstream products of 4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione?

For 4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, Downstream Products: 7-Ethyl-10-hydroxycamptothecin, Camptothecin, Rubitecan.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione (CAS 102978-40-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959403-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.