Dimethyl L-glutamate

Also known as: (S)-Dimethyl 2-aminopentanedioate, dimethyl glutamate, glutamic acid dimethyl ester, L-glutamic acid dimethyl ester, dimethyl L-glutamate, 1,5-Dimethyl (2S)-2-aminopentanedioate, (S)-2-Amino-4-(methoxycarbonyl)butyric acid methyl ester, (S)-4-(Methoxycarbonyl)-2-aminobutyric acid methyl ester, Einecs 229-414-1

Dimethyl L-glutamate (CAS 6525-53-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C7H13NO4 and a molecular weight of 175.18200 g/mol. Key properties include a boiling point of 224.292ºC at 760 mmHg, a density of 1.129 g/cm3 and a flash point of 76.674ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 6525-53-7
Jingsj CID: J-1957029-7
Molecular Formula: C₇H₁₃NO₄
Molecular Weight: 175.18200 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	224.292ºC at 760 mmHg
Density	1.129 g/cm3
Flash Point	76.674ºC
Exact Mass	175.08400
PSA	78.62000
LogP	0.14020

Activity & Biological Data

Target	KATP channel[4]
Additional Information	[1]. J Cancelas, et al. Potentiation by glutamic acid dimethyl ester of GLP-1 insulinotropic action in fed anaesthetized rats. Int J Mol Med. 2001 Nov;8(5):531-2. [2]. Sener A, et al. Insulinotropic action of glutamic acid dimethyl ester. American Journal of Physiology-Endocrinology and Metabolism, 1994, 267(4): E573-E584. [3]. I S Owens, et al. Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester. J Protozool. 1969 May;16(2):211-5. [4]. Hidenori Katsuta, et al. Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. Biochem Biophys Res Commun. 2003 Nov 21;311(3):660-4.

Target

KATP channel[4]

Additional Information

[1]. J Cancelas, et al. Potentiation by glutamic acid dimethyl ester of GLP-1 insulinotropic action in fed anaesthetized rats. Int J Mol Med. 2001 Nov;8(5):531-2. [2]. Sener A, et al. Insulinotropic action of glutamic acid dimethyl ester. American Journal of Physiology-Endocrinology and Metabolism, 1994, 267(4): E573-E584. [3]. I S Owens, et al. Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester. J Protozool. 1969 May;16(2):211-5. [4]. Hidenori Katsuta, et al. Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. Biochem Biophys Res Commun. 2003 Nov 21;311(3):660-4.

Frequently Asked Questions

What is the CAS number of Dimethyl L-glutamate?

The CAS number of Dimethyl L-glutamate is 6525-53-7.

What are the molecular formula and molecular weight of Dimethyl L-glutamate?

Dimethyl L-glutamate has molecular formula C7H13NO4 and molecular weight 175.18200 g/mol.

What are the upstream and downstream products of Dimethyl L-glutamate?

For Dimethyl L-glutamate, Upstream Products: Methanol, L-Glutamic acid, L-Glutamic acid 5-methyl ester; Downstream Products: Methyl L-pyroglutamate, Methyl (2S)-2-(bis(tert-butoxycarbonyl)amino)-5-oxopentanoate, tert-butyl (S)-piperidin-3-ylcarbamate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Dimethyl L-glutamate (CAS 6525-53-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1957029-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.