LY2334737

Also known as: 2'-Deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)cytidine, Cytidine, 2'-deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)-, LY 2334737, LY-2334737, LY2334737, 10 mM in DMSO, N-(1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-2-propylpentanamide, N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-propylpentanamide, N-{1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}-2-propylpentanamide, anticancer,HEV,Gemcitabine,HEVs,HRVs,LY 2334737,EV-A71,Rhinovirus,inhibit,Nucleoside Antimetabolite/Analog,Enterovirus,HRV,orally,LY2334737,LY-2334737,antiviral,Inhibitor, unii-ylr364xysa

LY2334737 (CAS 892128-60-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H25F2N3O5 and a molecular weight of 389.39400 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 892128-60-8
Jingsj CID: J-1956763-6
Molecular Formula: C₁₇H₂₅F₂N₃O₅
Molecular Weight: 389.39400 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	389.17600
PSA	117.17000
LogP	1.11830
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. Pratt SE, et al. Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells. Clin Cancer Res. 2013 Mar 1;19(5):1159-68. [2]. Koolen SL, et al. Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors. Clin Cancer Res. 2011 Sep 15;17(18):6071-82. [3]. Francia G, et al. Low-dose metronomic oral dosing of a prodrug of gemcitabine (LY2334737) causes antitumor effects in the absence of inhibition of systemic vasculogenesis. Mol Cancer Ther. 2012 Mar;11(3):680-9.

Additional Information

[1]. Pratt SE, et al. Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells. Clin Cancer Res. 2013 Mar 1;19(5):1159-68. [2]. Koolen SL, et al. Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors. Clin Cancer Res. 2011 Sep 15;17(18):6071-82. [3]. Francia G, et al. Low-dose metronomic oral dosing of a prodrug of gemcitabine (LY2334737) causes antitumor effects in the absence of inhibition of systemic vasculogenesis. Mol Cancer Ther. 2012 Mar;11(3):680-9.

Frequently Asked Questions

What is the CAS number of LY2334737?

The CAS number of LY2334737 is 892128-60-8.

What are the molecular formula and molecular weight of LY2334737?

LY2334737 has molecular formula C17H25F2N3O5 and molecular weight 389.39400 g/mol.

What are the upstream and downstream products of LY2334737?

For LY2334737, Downstream Products: Gemcitabine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "LY2334737 (CAS 892128-60-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956763-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.