cis-Tadalafil
Also known as: (6R,12aS)-Tadalafil, Tadalafil EP Impurity A, 12-epi-Tadalafil, 6R,12S-Tadalafil, cis-ent-Tadalafil, UNII-E319TQ0B6R, PYR403, (6R,12aS)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
cis-Tadalafil (CAS 171596-27-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H19N3O4 and a molecular weight of 389.40 g/mol. Key properties include a melting point of 295-296 ºC and a density of 1.51±0.1 g/cm3 (20 ºC 760 Torr). No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 171596-27-3
- Jingsj CID
- J-1956593-6
- Molecular Formula
- C22H19N3O4
- Molecular Weight
- 389.40 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 295-296 ºC |
|---|---|
| Density | 1.51±0.1 g/cm3 (20 ºC 760 Torr) |
| Exact Mass | 389.13800 |
| PSA | 74.87000 |
| LogP | 2.08710 |
| Additional Property | Insuluble (8.6E-3 g/L) (25 ºC) |
Activity & Biological Data
| Target | PDE5:0.09 μM (IC50) |
|---|---|
| Additional Information | [1]. Daugan A, et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues. J Med Chem. 2003 Oct 9;46(21):4533-42. |
Frequently Asked Questions
What is the CAS number of cis-Tadalafil?
The CAS number of cis-Tadalafil is 171596-27-3.
What are the molecular formula and molecular weight of cis-Tadalafil?
cis-Tadalafil has molecular formula C22H19N3O4 and molecular weight 389.40 g/mol.
What are the upstream and downstream products of cis-Tadalafil?
For cis-Tadalafil, Upstream Products: Tadalafil, Chloropretadalafil, Methyl L-tryptophanate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "cis-Tadalafil (CAS 171596-27-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956593-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.