Tadalafil
Also known as: Cialis, Adcirca, IC 351, IC351, GF 196960, GF-196960X, UK 336017, Tildenafil, Tadanafil, Tadalafei, (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, (6R,12aR)-6-(benzo[d][1,3]dioxol-5-yl)-2-methyl-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-, MFCD07771966
Tadalafil (CAS 171596-29-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H19N3O4 and a molecular weight of 389.404 g/mol. Key properties include a melting point of 298-300ºC, a boiling point of 679.1±55.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 364.5±31.5 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H302 — Harmful if swallowed and H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 171596-29-5
- Jingsj CID
- J-1955718-7
- Molecular Formula
- C22H19N3O4
- Molecular Weight
- 389.404 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 298-300ºC |
|---|---|
| Boiling Point | 679.1±55.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 364.5±31.5 °C |
| Exact Mass | 389.137543 |
| PSA | 74.87000 |
| LogP | 1.43 |
| Vapor Pressure | 0.0±2.1 mmHg at 25°C |
| Refractive Index | 1.758 |
| Storage Conditions | Hygroscopic, -20?C Freezer, Under Inert Atmosphere |
GHS Safety & Compliance
- H225 — Highly flammable liquid and vapour
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
- H332 — Harmful if inhaled
- H319 — Causes serious eye irritation
Activity & Biological Data
| Additional Information | [1]. Blount MA, et al. Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency,specificity, heterogeneity, and cGMP stimulation. Mol Pharmacol. 2004 Jul;66(1):144-52. [2]. Yang Y, et al. Effect of acute tadalafil on sperm motility and acrosome reaction: in vitro and in vivo studies. Andrologia. 2013 Apr 14. [Epub ahead of print] [3]. Mostafa ME, et al. Effect of Chronic Low-dose Tadalafil on Penile Cavernous Tissues in Diabetic Rats. Urology. 2013 Jun;81(6):1253-60. |
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Frequently Asked Questions
What is the CAS number of Tadalafil?
The CAS number of Tadalafil is 171596-29-5.
What are the molecular formula and molecular weight of Tadalafil?
Tadalafil has molecular formula C22H19N3O4 and molecular weight 389.404 g/mol.
Is Tadalafil hazardous?
Tadalafil has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H302 — Harmful if swallowed; H312 — Harmful in contact with skin.
What are the upstream and downstream products of Tadalafil?
For Tadalafil, Upstream Products: Chloropretadalafil, D-Tryptophan methyl ester hydrochloride, Ethyl sarcosinate hydrochloride; Downstream Products: cis-Tadalafil.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Tadalafil (CAS 171596-29-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955718-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.