Masitinib mesylate

Also known as: AB1010 mesylate, Masivet mesylate, N-(4-methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide methanesulfonate, 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide methanesulfonate

Masitinib mesylate (CAS 1048007-93-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C29H34N6O4S2 and a molecular weight of 594.74800 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1048007-93-7
Jingsj CID: J-1956115-0
Molecular Formula: C₂₉H₃₄N₆O₄S₂
Molecular Weight: 594.74800 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	594.20800
PSA	167.61000
LogP	5.21230
Storage Conditions	2-8℃

Activity & Biological Data

Target	IC50: 200 nM (Kit), 540 nM (PDGFRα), 800 nM (PDGFRβ)
Additional Information	[1]. Dubreuil P, et al. Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT. PLoS One, 2009, 4(9), e7258. [2]. Lawrence J, et al. Masitinib demonstrates anti-proliferative and pro-apoptotic activity in primary and metastatic feline injection-site sarcoma cells. Vet Comp Oncol, 2011, doi: 10.1111/j.1476-5829.2011.00291.x. [3]. Hahn KA, et al. Masitinib is safe and effective for the treatment of canine mast cell tumors. J Vet Intern Med, 2008, 22(6), 1301-1309. [4]. Humbert M, et al. Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model. PLoS One. 2010 Mar 4;5(3):e9430.

Target

IC50: 200 nM (Kit), 540 nM (PDGFRα), 800 nM (PDGFRβ)

Additional Information

[1]. Dubreuil P, et al. Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT. PLoS One, 2009, 4(9), e7258. [2]. Lawrence J, et al. Masitinib demonstrates anti-proliferative and pro-apoptotic activity in primary and metastatic feline injection-site sarcoma cells. Vet Comp Oncol, 2011, doi: 10.1111/j.1476-5829.2011.00291.x. [3]. Hahn KA, et al. Masitinib is safe and effective for the treatment of canine mast cell tumors. J Vet Intern Med, 2008, 22(6), 1301-1309. [4]. Humbert M, et al. Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model. PLoS One. 2010 Mar 4;5(3):e9430.

Frequently Asked Questions

What is the CAS number of Masitinib mesylate?

The CAS number of Masitinib mesylate is 1048007-93-7.

What are the molecular formula and molecular weight of Masitinib mesylate?

Masitinib mesylate has molecular formula C29H34N6O4S2 and molecular weight 594.74800 g/mol.

What are the upstream and downstream products of Masitinib mesylate?

For Masitinib mesylate, Upstream Products: Masitinib, Methanesulfonic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Masitinib mesylate (CAS 1048007-93-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956115-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.