Alsterpaullone
Also known as: 9-Nitro-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one, 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one, 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one, Indolo[3,2-d][1]benzazepin-6(5H)-one, 7,12-dihydro-9-nitro-, 9-Nitropaullone, NSC 705701
Alsterpaullone (CAS 237430-03-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H11N3O3 and a molecular weight of 293.277 g/mol. Key properties include a boiling point of 651.5±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 347.8±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 237430-03-4
- Jingsj CID
- J-1956001-1
- Molecular Formula
- C16H11N3O3
- Molecular Weight
- 293.277 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 651.5±45.0 °C at 760 mmHg |
|---|---|
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 347.8±28.7 °C |
| Exact Mass | 293.080048 |
| PSA | 90.71000 |
| LogP | 3.55 |
| Vapor Pressure | 0.0±2.0 mmHg at 25°C |
| Refractive Index | 1.738 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Cdk1/cyclin B:35 nM (IC50) cdk2/cyclin A:15 nM (IC50) CDK2/Cyc E:200 nM (IC50) CDK5/p35:40 nM (IC50) GSK-3α:4 (IC50) GSK-3β:4 nM (IC50) |
|---|---|
| Additional Information | [1]. Leost M, et al. Paullones are potent inhibitors of glycogen synthase kinase-3beta and cyclin-dependent kinase 5/p25. Eur J Biochem. 2000 Oct;267(19):5983-94. [2]. Lahusen T, et al. Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Mol Carcinog. 2003 Apr;36(4):183-94. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Alsterpaullone?
The CAS number of Alsterpaullone is 237430-03-4.
What are the molecular formula and molecular weight of Alsterpaullone?
Alsterpaullone has molecular formula C16H11N3O3 and molecular weight 293.277 g/mol.
Is Alsterpaullone hazardous?
Alsterpaullone has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Alsterpaullone?
For Alsterpaullone, Upstream Products: 3,4-dihydro-1H-1-benzazepine-2,5-dione, 4-Nitrophenylhydrazine hydrochloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Alsterpaullone (CAS 237430-03-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1956001-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.