5,7-Dimethoxyflavone

Also known as: Chrysin dimethylether, Chrysin 5,7-dimethyl ether, Dimethylchrysin, 5,7-dimethoxy-2-phenyl-4H-chromen-4-one, 5,7-Dimethoxy-2-phenyl-4H-1-benzopyran-4-one, Chrysin DME

5,7-Dimethoxyflavone (CAS 21392-57-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C17H14O4 and a molecular weight of 282.291 g/mol. Key properties include a melting point of 150-152ºC, a boiling point of 476.6±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 213.4±28.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 21392-57-4
Jingsj CID: J-1955557-8
Molecular Formula: C₁₇H₁₄O₄
Molecular Weight: 282.291 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	150-152ºC
Boiling Point	476.6±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	213.4±28.8 °C
Exact Mass	282.089203
PSA	48.67000
LogP	3.27
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.598

Activity & Biological Data

Target	CYP3A Breast Cancer Resistance Protein (BCRP)
Additional Information	[1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34.

Customs & Trade Information

HS Code	2914509090
Summary	HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 5,7-Dimethoxyflavone?

The CAS number of 5,7-Dimethoxyflavone is 21392-57-4.

What are the molecular formula and molecular weight of 5,7-Dimethoxyflavone?

5,7-Dimethoxyflavone has molecular formula C17H14O4 and molecular weight 282.291 g/mol.

What are the upstream and downstream products of 5,7-Dimethoxyflavone?

For 5,7-Dimethoxyflavone, Upstream Products: Chrysin, iodomethane, Flavokawain B; Downstream Products: Chrysin, 5,6,7-Trimethoxyflavone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5,7-Dimethoxyflavone (CAS 21392-57-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955557-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.