Flosulide

Also known as: Flosulide, CGP-28238, CGP-28328, Flosulida, Flosulida [INN-Spanish], Flosulidum, Flosulidum [INN-Latin], Methanesulfonamide, N-[6-(2,4-difluorophenoxy)-2,3-dihydro-1-oxo-1H-inden-5-yl]-, N-(6-(2,4-Difluorophenoxy)-1-oxo-5-indanyl)methanesulfonamide, N-[1-Oxo-6-(2,4-difluorophenoxy)indan-5-yl]methanesulfonamide, N-[6-(2,4-Difluoro-phenoxy)-1-oxo-indan-5-yl]-methanesulfonamide, N-[6-(2,4-difluorophenoxy)-1-oxo-2,3-dihydroinden-5-yl]methanesulfonamide, N-[6-(2,4-difluorophenoxy)-2,3-dihydro-1-oxo-1H-inden-5-yl]methanesulfonamide, N-[[6-(2,4-Difluorophenoxy)-2,3-dihydro-1-oxo-1H-inden]-5-yl]methanesulfonamide, ZK-38997, 5-methanesulfonamido-6-((2,4-difluorophenyl)oxy)-1-indanone, 6-(2,4-difluorophenoxy)-5-methylsulfonylamino-1-indanone

Flosulide (CAS 80937-31-1) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C16H13F2NO4S and a molecular weight of 353.34100 g/mol. Key properties include a boiling point of 446.9ºC at 760 mmHg, a density of 1.506g/cm3 and a flash point of 224.1ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 80937-31-1
Jingsj CID: J-1955512-8
Molecular Formula: C₁₆H₁₃F₂NO₄S
Molecular Weight: 353.34100 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	446.9ºC at 760 mmHg
Density	1.506g/cm3
Flash Point	224.1ºC
Exact Mass	353.05300
PSA	80.85000
LogP	4.41130
Refractive Index	1.62
Storage Conditions	2-8℃

Activity & Biological Data

Target	COX-2
Additional Information	[1]. Turull A, et al. Acute effects of the anti-inflammatory cyclooxygenase-2 selective inhibitor, flosulide, on renal plasma flow and glomerular filtration rate in rats. Inflammation. 2001 Apr;25(2):119-28. [2]. Zimmermann KC, et al. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res. 1999 Jan 1;59(1):198-204. [3]. Heise G, et al. Different actions of the cyclooxygenase 2 selective inhibitor flosulide in rats with passive Heymann nephritis. Nephron. 1998 Oct;80(2):220-6.

Target

COX-2

Additional Information

[1]. Turull A, et al. Acute effects of the anti-inflammatory cyclooxygenase-2 selective inhibitor, flosulide, on renal plasma flow and glomerular filtration rate in rats. Inflammation. 2001 Apr;25(2):119-28. [2]. Zimmermann KC, et al. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res. 1999 Jan 1;59(1):198-204. [3]. Heise G, et al. Different actions of the cyclooxygenase 2 selective inhibitor flosulide in rats with passive Heymann nephritis. Nephron. 1998 Oct;80(2):220-6.

Frequently Asked Questions

What is the CAS number of Flosulide?

The CAS number of Flosulide is 80937-31-1.

What are the molecular formula and molecular weight of Flosulide?

Flosulide has molecular formula C16H13F2NO4S and molecular weight 353.34100 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Flosulide (CAS 80937-31-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1955512-8 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.